Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2170900 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2CES2CES1 | |
| Acetic Acid SCHEMBL6755875 | 0.96 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2CES2CES1 | |
| Succinic Acid SCHEMBL1704049 | 0.89 | CA1 (0.38) | ALDH1A1LMNASMN1; SMN2CES2CES1 | |
| Acetic Acid SCHEMBL9067963 | 0.85 | SLC6A4 (0.38) | ALDH1A1LMNASMN1; SMN2CES2CES1 | |
| Iodide SCHEMBL7192916 | 0.83 | ACHE (0.42) | ALDH1A1LMNASMN1; SMN2TDP1ACHE | |
| Bromide SCHEMBL5074601 | 0.83 | ACHE (0.42) | ALDH1A1LMNASMN1; SMN2TDP1ACHE | |
| Hydrochloric Acid SCHEMBL7196441 | 0.83 | ACHE (0.42) | ALDH1A1LMNASMN1; SMN2TDP1ACHE | |
| Phosphoric Acid SCHEMBL7193240 | 0.82 | LMNA (0.40) | ALDH1A1LMNATDP1ACHETSHR | |
| Acetic Acid SCHEMBL328882 | 0.82 | TSHR (0.48) | ALDH1A1LMNASMN1; SMN2CES2CES1 | |
| Acetic Acid SCHEMBL133341 | 0.82 | TSHR (0.48) | ALDH1A1LMNASMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0624173-B1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 1997-04-02 | — | — | EP | claimed |
| US-5360886-A | Alklyphenylphosphine or phosphonium catalyst | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | claimed |
| US-5310853-A | Epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | claimed |
| EP-3017001-B1 | CURABLE COMPOSITION AND PROCESS FOR THE MANUFACTURE OF AN EPOXY THERMOSET | RHODIA OPERATIONS (FR) | 2019-06-19 | — | — | EP | disclosed |
| US-10077332-B2 | Curable composition and process for the manufacture of an epoxy thermoset | RHODIA OPERATIONS (FR) | 2018-09-18 | — | — | US | disclosed |
| US-20160152764-A1 | Curable composition and process for the manufacture of an epoxy thermoset | SPECIALTY OPERATIONS FRANCE (FR) | 2016-06-02 | — | — | US | disclosed |
| EP-3017001-A1 | CURABLE COMPOSITION AND PROCESS FOR THE MANUFACTURE OF AN EPOXY THERMOSET | Rhodia Operations (FR) | 2016-05-11 | — | — | EP | disclosed |
| EP-2829570-A1 | Curable composition and process for the manufacture of an epoxy thermoset | Rhodia Operations (FR) | 2015-01-28 | — | — | EP | disclosed |
| WO-2015001061-A1 | CURABLE COMPOSITION AND PROCESS FOR THE MANUFACTURE OF AN EPOXY THERMOSET | RHODIA OPERATIONS (FR) | 2015-01-08 | — | — | WO | disclosed |
| EP-1307497-A2 | EPOXY RESINS AND PROCESS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-0624173-B2 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002000755-A2 | EPOXY RESING AND PROCESS FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| EP-0624173-B1 | PRECATALYZED CATALYST COMPOSITIONS, PROCESS FOR PREPARING RESINS | DOW CHEMICAL CO (US) | 1997-04-02 | — | — | EP | disclosed |
| US-5360886-A | Alklyphenylphosphine or phosphonium catalyst | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| US-5310853-A | Epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| US-5202407-A | Phosphonium or phosphine catalyst having at least three alkylphenyl groups attached to phosphorus atom | THE DOW CHEMICAL COMPANY (US) | 1993-04-13 | — | — | US | disclosed |