SCHEMBL5075137

SCHEMBL5075137

COCC(CO[Si](C)(C)CCc1ccccc1)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
LMNA P02545 5/20 0.33
SLC6A2 P23975 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
GAA P10253 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP2D6 P10635 2/20 0.31
MMP8 P22894 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081735 0.94 TAAR1 (0.36) LMNASLC6A2TAAR1NPC1RAB9A
SCHEMBL5078138 0.88 SLC6A2 (0.33) LMNASLC6A2TAAR1CYP2D6CYP1A2
SCHEMBL5077356 0.86 ALDH1A1 (0.37) L3MBTL1TP53POLBSLC6A2TAAR1
SCHEMBL5085457 0.86 SLC6A2 (0.31) SLC6A2TAAR1
SCHEMBL5078348 0.85 SLC6A2 (0.34) LMNASLC6A2TAAR1CYP2D6CYP1A2
SCHEMBL5081510 0.85 SLC6A2 (0.34) TP53LMNASLC6A2TAAR1ALDH1A1
SCHEMBL5078344 0.85 NPC1 (0.33) L3MBTL1TP53POLBTSHRLMNA
SCHEMBL5075136 0.83 SMN1; SMN2 (0.33) POLBNPC1RAB9ASMN1; SMN2GAA
SCHEMBL5075212 0.83 SPHK2 (0.35) POLBLMNASLC6A2NPC1RAB9A
SCHEMBL5077173 0.83 SLC6A2 (0.37) TP53LMNASLC6A2TAAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed