Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998030 | 0.88 | SRD5A2 (0.68) | LMNAHTTMAPTPKMSIRT1 | |
| SCHEMBL7482370 | 0.86 | SRD5A2 (0.70) | LMNAHTTMAPTPKMESR1 | |
| SCHEMBL23396621 | 0.86 | SRD5A2 (0.70) | LMNAHTTMAPTPKMESR1 | |
| SCHEMBL16179592 | 0.85 | GABRA1 (0.52) | MAPTPKMSIRT1SRD5A2SMN1; SMN2 | |
| SCHEMBL5075836 | 0.85 | ELANE (0.50) | LMNAHTTMAPTPKMESR1 | |
| SCHEMBL27510569 | 0.82 | ALDH1A1 (0.56) | MAPTPKMSIRT1SRD5A2SMN1; SMN2 | |
| SCHEMBL5712200 | 0.81 | SIRT1 (0.66) | LMNAHTTMAPTPKMESR1 | |
| SCHEMBL15685927 | 0.81 | LMNA (0.61) | LMNAHTTMAPTPKMSIRT1 | |
| SCHEMBL5075015 | 0.80 | MAPT (0.58) | LMNAHTTMAPTHPGDSIRT1 | |
| SCHEMBL21867671 | 0.80 | SIRT1 (0.65) | LMNAHTTMAPTPKMESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359176-B1 | Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups | BAYER MATERIALSCIENCE AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| US-6825312-B2 | POLYCARBONATESTER COPOLYMER MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| US-20040030090-A1 | Polycarbonates, polyester carbonates and polyesters with special branched terminal groups | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-12 | — | — | US | disclosed |
| EP-1359176-A2 | Polycarbonates, polyestercarbonates and polyesters having specific branched endgroups | Bayer Aktiengesellschaft (DE) | 2003-11-05 | — | — | EP | disclosed |