Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29559243 | 0.98 | SLC9A1 (0.38) | HTTSLC9A1CYP2A6ADRA2AADRA2B | |
| SCHEMBL96020 | 0.79 | ADRA2A (0.38) | CYP2A6ADRA2AADRA2BHTR1ADRD2 | |
| SCHEMBL1062508 | 0.72 | CYP2A6 (0.56) | CYP2A6CA1CA2TSHRMAPT | |
| SCHEMBL35430448 | 0.72 | CYP2A6 (0.56) | CYP2A6CA1CA2TSHRMAPT | |
| SCHEMBL45954 | 0.71 | CA1 (0.54) | HTTCA1CA2ALDH1A1TSHR | |
| SCHEMBL29489124 | 0.71 | CA1 (0.54) | HTTCA1CA2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29915059 | 0.71 | CYP2A6 (0.55) | CYP2A6CA1CA2MAPTIMPDH2 | |
| SCHEMBL3789708 | 0.71 | TRPA1 (0.46) | HTTCYP2A6ADRA2AADRA2BALDH1A1 | |
| SCHEMBL18879651 | 0.71 | KDM4E (0.38) | CYP2A6ALDH1A1TSHRKDM4EGAA | |
| SCHEMBL2264338 | 0.71 | CYP19A1 (0.43) | CYP2A6ADRA2AADRA2BALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | Clear Creek Bio, Inc. (US) | 2025-01-23 | — | — | US | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| CN-110286112-B | Raman probe and preparation method and application thereof | 上海交通大学 | 2022-01-14 | — | — | CN | disclosed |
| US-10294212-B2 | Inhibitors of the kynurenine pathway | CURADEV PHARMA, PVT. LTD. (IN) | 2019-05-21 | — | — | US | disclosed |
| CN-109678755-A | It is a kind of using formamide as the preparation method of the fragrant nitrile in cyanogen source | 湘潭大学 | 2019-04-26 | — | — | CN | disclosed |
| EP-2970173-B1 | INHIBITORS OF THE KYNURENINE PATHWAY | CURADEV PHARMA PRIVATE LTD (IN) | 2018-05-09 | — | — | EP | disclosed |
| US-20180030026-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | CURADEV PHARMA PVT LTD | 2018-02-01 | — | — | US | disclosed |
| US-20180030026-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | CURADEV PHARMA PVT LTD | 2018-02-01 | — | — | US | disclosed |
| US-9815811-B2 | Inhibitors of the kynurenine pathway | CURADEV PHARMA, PVT. LTD. (IN) | 2017-11-14 | — | — | US | disclosed |
| US-9815811-B2 | Inhibitors of the kynurenine pathway | CURADEV PHARMA, PVT. LTD. (IN) | 2017-11-14 | — | — | US | disclosed |
| EP-0902013-B1 | Novel amidine derivatives, their preparation and their use as medicaments with LTB-4 antagonistic effect | BOEHRINGER INGELHEIM INT (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001068653-A1 | DIHYDROIMIDAZO[2,1-B]THIAZOLE AND DIHYDRO-5H-THIAZOLO[3,2-A]PYRIMIDINES AS ANTIDEPRESSANT AGENTS | KNOLL GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
| EP-1067128-A1 | FUSED THIOPHENE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-6037377-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS | BOEHRINGER INGELHEIM KG (DE) | 2000-03-14 | — | — | US | disclosed |
| EP-0625138-B1 | NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS WITH LTB4 ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM INT (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0902013-A1 | Novel amidine derivatives, their preparation and their use as medicaments with LTB-4 antagonistic effect | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1999-03-17 | — | — | EP | disclosed |
| EP-0625138-A1 | NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDIAMENTS WITH LTB-4 ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1994-11-23 | — | — | EP | disclosed |
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |
| WO-1993016036-A1 | NOVEL AMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDIAMENTS WITH LTB-4 ANTAGONISTIC EFFECT | BOEHRINGER INGELHEIM KG (DE) | 1993-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294212-B2 | Inhibitors of the kynurenine pathway | IDO1, IDO2, KYNU | HTT 2003/4885SLC9A1 1958/4885CYP2A6 132/4885 |
| US-20180030026-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | IDO1, IDO2, KYNU | HTT 2003/4885SLC9A1 1958/4885CYP2A6 132/4885 |
| US-20250025443-A1 | COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES | ACE, PREP, PEPD | HTT 2553/4885SLC9A1 3764/4885CYP2A6 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.