SCHEMBL5075817

SCHEMBL5075817

O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.39
MMP9 P14780 3/20 0.39
CYP2C9 P11712 2/20 0.39
BLM P54132 2/20 0.39
PMP22 Q01453 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CACNA1F O60840 1/20 0.39
MAPT P10636 1/20 0.39
HTR2A P28223 1/20 0.39
HRH1 P35367 1/20 0.39
SCN1A P35498 1/20 0.39
SCN4A P35499 1/20 0.39
CACNA1D Q01668 1/20 0.39
KCNH2 Q12809 1/20 0.39
CACNA1S Q13698 1/20 0.39
CACNA1C Q13936 1/20 0.39
SCN5A Q14524 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
LMNA P02545 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10712315 0.78 CYP2C9 (0.38) MMP2MMP9CYP2C9BLMPMP22
SCHEMBL14353736 0.75 ALDH1A1 (0.42) MMP2MMP9CYP2C9BLMPMP22
SCHEMBL15461429 0.75 PKM (0.47) MMP2MMP9CYP2C9BLMPMP22
SCHEMBL10335825 0.75 MMP3 (0.41) MMP2MMP9CYP2C9BLMPMP22
SCHEMBL15463104 0.73 TDP1 (0.40) MMP2MMP9CYP2C9BLMPMP22
SCHEMBL14400476 0.73 CYP2C19 (0.48) MMP2MMP9ALDH1A1MAPTLMNA
SCHEMBL15461426 0.71 ADRA1B (0.47) MMP2MMP9MAPTLMNACYP2C19
SCHEMBL9818448 0.69 PKM (0.34) CYP2C9ALDH1A1MAPTLMNACYP2C19
SCHEMBL1571746 0.68 ADRA1B (0.45) MMP2MMP9CYP2C9BLMPMP22
SCHEMBL11304673 0.68 ADRA1B (0.48) LMNAMMP3MMP8ADRA1BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905237-B2 Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation THE CHINESE UNIVERSITY OF HONG KONG (CN) 2024-02-20 US claimed
CN-108866605-A A kind of Zn-Ni-Al2O3Electroplate liquid, preparation method and application 东北大学 2018-11-23 CN claimed
CN-108866606-A A kind of alkaline non-cyanide Zn-Ni-Al2O3Electroplate liquid, preparation method and application 东北大学 2018-11-23 CN claimed
CN-108866605-A A kind of Zn-Ni-Al2O3Electroplate liquid, preparation method and application 东北大学 2018-11-23 CN disclosed
CN-108866606-A A kind of alkaline non-cyanide Zn-Ni-Al2O3Electroplate liquid, preparation method and application 东北大学 2018-11-23 CN disclosed
EP-1968380-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE Sanderson, William D. (US) 2008-09-17 EP disclosed
WO-2007078838-A2 SOLID BIOCIDE COMPOSITION AND SEALED BIOCIDE ARTICLE SANDERSON WILLIAM D (US) 2007-07-12 WO disclosed