Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358251 | 0.81 | NPSR1 (0.33) | PKMNPSR1ELANEALDH1A1F2 | |
| SCHEMBL4125062 | 0.81 | NPSR1 (0.33) | PKMNPSR1ELANEALDH1A1F2 | |
| SCHEMBL10636113 | 0.81 | ELANE (0.36) | PKMELANEF2CTSGCMA1 | |
| SCHEMBL763669 | 0.70 | PKM (0.38) | PKMELANEALDH1A1F2PLG | |
| SCHEMBL5075817 | 0.69 | MMP2 (0.39) | PKMNPSR1ALDH1A1LMNATDP1 | |
| Iodobenzene SCHEMBL10799601 | 0.66 | ELANE (0.35) | NPSR1ELANEALDH1A1CTSG | |
| SCHEMBL17830174 | 0.64 | HTR1A (0.46) | PKMALDH1A1LMNARENAPP | |
| SCHEMBL4732888 | 0.64 | PKM (0.34) | PKMNPSR1ALDH1A1LMNAREN | |
| SCHEMBL19923635 | 0.62 | ELANE (0.53) | NPSR1ELANEF2PLGCTSG | |
| SCHEMBL19923463 | 0.62 | ELANE (0.46) | ELANEALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11905237-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-02-20 | — | — | US | claimed |
| CN-109686990-B | Preparation method and application of Ni-Zn/nitrogen-sulfur double-doped three-dimensional graphene electrode material | 东北大学 | 2020-11-24 | — | — | CN | claimed |
| US-20130005786-A1 | THERAPEUTIC INVENTION | KAPOOR RAJU (GB) | 2013-01-03 | — | — | US | claimed |
| US-12637403-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2026-05-26 | — | — | US | disclosed |
| EP-3551182-B1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -)AN ALGESIC FOR THE TREATMENT OF CHRONIC PAIN | TOPICAL INNOVATIONS B V (NL) | 2025-03-19 | — | — | EP | disclosed |
| EP-3551166-B1 | TOPICAL PHENYTOIN FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN | TOPICAL INNOVATIONS B V (NL) | 2024-08-21 | — | — | EP | disclosed |
| US-20240166586-A1 | ACCESS TO CHIRAL BISPHENOL (BPOL) LIGANDS THROUGH DESYMMETRIZING ASYMMETRIC ORTHO-SELECTIVE MONO-HALOGENATION | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-05-23 | — | — | US | disclosed |
| CN-117886858-A | Ammonium phosphate compound and preparation method and application thereof | 南昌大学 | 2024-04-16 | — | — | CN | disclosed |
| US-11905237-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2024-02-20 | — | — | US | disclosed |
| US-11285099-B2 | Topical phenytoin for use in the treatment of peripheral neuropathic pain | TOPICAL INNOVATIONS B.V. (NL) | 2022-03-29 | — | — | US | disclosed |
| US-11147799-B2 | Topical pharmaceutical composition containing phenytoin and a (co-) analgesic for the treatment of chronic pain | Keppel Hesselink, Jan Marius (NL) | 2021-10-19 | — | — | US | disclosed |
| US-20200069649-A1 | TOPICAL PHARMACEUTICAL COMPOSITION CONTAINING PHENYTOIN AND A (CO -) ANALGESIC FOR THE TREATMENT OF CHRONIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2020-03-05 | — | — | US | disclosed |
| EP-3551166-A1 | TOPICAL PHENYTOIN FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN | TOPICAL INNOVATIONS B.V. (NL) | 2019-10-16 | — | — | EP | disclosed |
| WO-2018106107-A1 | TOPICAL PHENYTOIN FOR USE IN THE TREATMENT OF PERIPHERAL NEUROPATHIC PAIN | KOPSKY DAVID JOS (NL) | 2018-06-14 | — | — | WO | disclosed |
| US-20130005786-A1 | THERAPEUTIC INVENTION | KAPOOR RAJU (GB) | 2013-01-03 | — | — | US | disclosed |
| EP-0177645-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED HYDANTOINS | LONZA INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| US-4654424-A | CONTROLLING PH | GLYCO INC. (US) | 1987-03-31 | — | — | US | disclosed |
| US-4560766-A | Shaped halogenated hydantoins | GLYCO CHEMICALS, INC. (US) | 1985-12-24 | — | — | US | disclosed |
| US-4242518-A | Thiophene compounds and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| US-4239897-A | Thiophene compounds and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637403-B2 | Access to chiral bisphenol (BPOL) ligands through desymmetrizing asymmetric ortho-selective mono-halogenation | NR4A1, BRPF3, BPTF | PKM 1180/4885NPSR1 443/4885ELANE 2820/4885 |
| US-20240166586-A1 | ACCESS TO CHIRAL BISPHENOL (BPOL) LIGANDS THROUGH DESYMMETRIZING ASYMMETRIC ORTHO-SELECTIVE MONO-HALOGENATION | OSBP, BICRA, BRPF3 | PKM 2824/4885NPSR1 411/4885ELANE 3382/4885 |
| US-20130005786-A1 | THERAPEUTIC INVENTION | AQP4, PMP22, NHERF1 | PKM 1650/4885NPSR1 1940/4885ELANE 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.