Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.44 |
| ▸ | NOS2 | P35228 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29755008 | 1.00 | KIF11 (0.50) | KIF11PNMTENPP2LOXL2TAAR1 | |
| Hydrochloric Acid SCHEMBL31072779 | 0.98 | KIF11 (0.49) | KIF11PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL4454237 | 0.85 | KIF11 (0.49) | KIF11PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL1908518 | 0.83 | ENPP2 (0.50) | KIF11PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL27476979 | 0.83 | KIF11 (0.47) | KIF11PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL12024583 | 0.83 | TAAR1 (0.52) | KIF11PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL28275380 | 0.83 | PNMT (0.50) | KIF11PNMTENPP2LOXL2TAAR1 | |
| SCHEMBL2911870 | 0.83 | TAAR1 (0.67) | KIF11LOXL2TAAR1NOS1MAOB | |
| SCHEMBL1653927 | 0.82 | KIF11 (0.49) | KIF11HTR2AHTR2CHTR2BBCHE | |
| SCHEMBL30573009 | 0.82 | KIF11 (0.49) | KIF11HTR2AHTR2CHTR2BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119140080-B | Titanium oxide film catalytic material for rapid high-yield synthesis of imine and preparation method and application thereof | 中国科学院理化技术研究所 | 2025-02-11 | — | — | CN | claimed |
| CN-119140080-A | Titanium oxide film catalytic material for rapid high-yield synthesis of imine and preparation method and application thereof | 中国科学院理化技术研究所 | 2024-12-17 | — | — | CN | claimed |
| EP-4153561-B1 | 9H-FLUOREN DERIVATES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | UNIV JAGIELLONSKI (PL) | 2026-04-29 | — | — | EP | disclosed |
| US-12492163-B2 | 9H-fluorene derivatives or their pharmaceutically acceptable salts | UNIWERSYTET JAGIELLONSKI (PL) | 2025-12-09 | — | — | US | disclosed |
| CN-119822990-A | Adamantane isopropanolamine structure compound and preparation method and application thereof | 贵州大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-119140080-B | Titanium oxide film catalytic material for rapid high-yield synthesis of imine and preparation method and application thereof | 中国科学院理化技术研究所 | 2025-02-11 | — | — | CN | disclosed |
| US-20250002452-A1 | BICYCLOPENTANE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2025-01-02 | — | — | US | disclosed |
| EP-4479377-A1 | NEW BICYCLOPENTANE DERIVATIVES | Icagen, LLC (US) | 2024-12-25 | — | — | EP | disclosed |
| CN-119140080-A | Titanium oxide film catalytic material for rapid high-yield synthesis of imine and preparation method and application thereof | 中国科学院理化技术研究所 | 2024-12-17 | — | — | CN | disclosed |
| US-20240051975-A1 | NOVEL NAMPT ENZYME AGONIST AND PREPARATION AND USE THEREOF | TSINGHUA UNIVERSITY (CN) | 2024-02-15 | — | — | US | disclosed |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2024-01-18 | — | — | US | disclosed |
| EP-1490340-A1 | HETEROAROMATIC UREA DERIVATIVES AS VR-1 RECEPTOR MODULATORS FOR TREATING PAIN | MERCK SHARP & DOHME LTD. (GB) | 2004-12-29 | — | — | EP | disclosed |
| EP-1477186-A1 | ANTIPRURITICS | SHIONOGI & CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6818640-B1 | BIND SELECTIVELY TO CANNABINOID 2 RECEPTOR; ANTIINFLAMMATORY AGENTS | SHIONOGI & CO., LTD. (JP) | 2004-11-16 | — | — | US | disclosed |
| CN-1514831-A | Medicinal composition containing 1,3-thiazine derivative | ��Ұ����ҩ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| US-20040116326-A1 | Medicinal composition containing 1,3-thiazine derivative | SHIONOGI & CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1375489-A1 | MEDICINAL COMPOSITION CONTAINING 1,3-THIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003080578-A1 | HETEROAROMATIC UREA DERIVATIVES AS VR-1 RECEPTOR MODULATORS FOR TREATING PAIN | MERCK SHARP & DOHME LIMITED (GB) | 2003-10-02 | — | — | WO | disclosed |
| CN-1387519-A | 2-imino-1, 3-thiazine derivatives | SHIONOGI & CO (JP) | 2002-12-25 | — | — | CN | disclosed |
| EP-1219612-A1 | 2-IMINO-1,3-THIAZINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002452-A1 | BICYCLOPENTANE DERIVATIVES | BICRA, C1R, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | KIF11 445/4885PNMT 4869/4885ENPP2 3961/4885 |
| US-20240051975-A1 | NOVEL NAMPT ENZYME AGONIST AND PREPARATION AND USE THEREOF | NAMPT, NAT1, SIRT1 | KIF11 2696/4885PNMT 391/4885ENPP2 980/4885 |
| US-20240018161-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | KIF11 4517/4885PNMT 3623/4885ENPP2 497/4885 |
| US-12492163-B2 | 9H-fluorene derivatives or their pharmaceutically acceptable salts | BACE1, BACE2, APP | KIF11 3851/4885PNMT 476/4885ENPP2 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.