Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345781 | 0.79 | TSHR (0.39) | KDM4ETSHRKMT2ACRBNALDH1A1 | |
| SCHEMBL4419292 | 0.78 | MAPT (0.43) | KDM4EMEN1KMT2ASMN1; SMN2CRBN | |
| SCHEMBL31377154 | 0.78 | APEX1 (0.42) | KDM4EALOX15TSHRSIRT1APEX1 | |
| Hydrochloric Acid SCHEMBL1371699 | 0.78 | TSHR (0.38) | KDM4ETSHRKMT2ACRBNALDH1A1 | |
| SCHEMBL2194813 | 0.77 | CRBN (0.44) | KDM4EMEN1KMT2ACRBNALDH1A1 | |
| SCHEMBL31377128 | 0.76 | ITGB3 (0.42) | KDM4EALOX15TSHRSIRT1APEX1 | |
| SCHEMBL21384017 | 0.76 | PDE7A (0.42) | KDM4ETSHRKMT2ASMN1; SMN2CRBN | |
| SCHEMBL4190795 | 0.74 | CRBN (0.46) | SMN1; SMN2CRBNALDH1A1PKMMAPT | |
| SCHEMBL10963440 | 0.74 | CRBN (0.46) | CRBNALDH1A1MAPTTDP1EPHX2 | |
| SCHEMBL11257635 | 0.74 | CRBN (0.46) | SMN1; SMN2CRBNALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119307477-A | Hydantoin enzymes and their use in hydrolyzing or preparing chiral monomer compounds | 上海合全药物研发有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | GALAPAGOS NV (BE) | 2023-08-08 | — | — | US | disclosed |
| CN-103243054-B | Carboxyethyl hydantoinase production strain and application thereof | NANJING TECH UNIVERSITY (CN) | 2014-10-29 | — | — | CN | disclosed |
| US-20080317689-A1 | Transdermal Preparation for External Use Containing Antiinflammatory/Analgesic Agent | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2008-12-25 | — | — | US | disclosed |
| US-6387359-B1 | N-LONG CHAIN ACYLAMINO ACID POLYGLYCERIN ESTERS; COSMETICS | AJINOMOTO CO., INC. (JP) | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | ADAMTS1, ADAMTS5, ADAMTS7 | KDM4E 569/4885ALOX15 1718/4885TSHR 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.