Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793731 | 1.00 | CA2 (0.39) | CA2LMNAZDHHC7CA1GRIK1 | |
| SCHEMBL4778464 | 0.85 | GRIK1 (0.34) | CA2LMNAZDHHC7CA1GRIK1 | |
| SCHEMBL19409983 | 0.77 | CA2 (0.52) | CA2LMNAGRIK1GRIK2GPR84 | |
| SCHEMBL129992 | 0.77 | CA2 (0.52) | CA2LMNAGRIK1GRIK2GPR84 | |
| SCHEMBL1282988 | 0.77 | CA2 (0.52) | CA2LMNAGRIK1GRIK2GPR84 | |
| SCHEMBL6391386 | 0.77 | GPR84 (0.46) | LMNAZDHHC7GPR84SPHK1FFAR1 | |
| SCHEMBL17148821 | 0.76 | LMNA (0.46) | LMNAZDHHC7SMPD1GPR84FDPS | |
| SCHEMBL10995430 | 0.73 | CA2 (0.48) | CA2LMNACA1GRIK1GRIK2 | |
| SCHEMBL15674875 | 0.73 | CA2 (0.48) | CA2LMNACA1GRIK1GRIK2 | |
| SCHEMBL6051331 | 0.73 | CA2 (0.48) | CA2LMNAGRIK1GRIK2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372384-B2 | Quaternary ammonium functionalized cross-linked polyalkylsiloxanes with anti-fouling activity | NDSU RESEARCH FOUNDATION (US) | 2013-02-12 | — | — | US | disclosed |
| EP-1819748-B1 | POLYURETHANE RESINS, A METHOD FOR THE PRODUCTION THEREOF AND OPTICAL LENSES MADE OF SAID RESINS | ESSILOR INT (FR) | 2008-10-29 | — | — | EP | disclosed |
| US-20080181862-A1 | Quaternary ammonium functionalized cross-linked polyalkylsiloxanes with anti-fouling activity | NDSU RESEARCH FOUNDATION | 2008-07-31 | — | — | US | disclosed |
| EP-1819748-A1 | POLYURETHANE RESINS, A METHOD FOR THE PRODUCTION THEREOF AND OPTICAL LENSES MADE OF SAID RESINS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006045960-A1 | POLYURETHANE RESINS, A METHOD FOR THE PRODUCTION THEREOF AND OPTICAL LENSES MADE OF SAID RESINS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181862-A1 | Quaternary ammonium functionalized cross-linked polyalkylsiloxanes with anti-fouling activity | PFAS, PIGS, ALG1 | CA2 368/4885LMNA 3512/4885ZDHHC7 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.