SCHEMBL5078722

SCHEMBL5078722

CCOCC(CO[Si](C)(C)Cc1ccccc1)(CC(C)C)CC(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081838 0.92 SIGMAR1 (0.33) SIGMAR1
SCHEMBL5075111 0.90 MAPT (0.32) MAPTSIGMAR1
SCHEMBL5078398 0.87 ALDH1A1 (0.33) ALDH1A1MAPTSIGMAR1
SCHEMBL5077729 0.86 TAAR1 (0.30) SIGMAR1
SCHEMBL5077300 0.85 ALDH1A1 (0.33) ALDH1A1
SCHEMBL5075131 0.81
SCHEMBL5081486 0.79 DUT (0.30)
SCHEMBL5075172 0.79 ALDH1A1 (0.38) ALDH1A1
SCHEMBL5077716 0.78
SCHEMBL5080899 0.77 NPC1 (0.35) ALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed