SCHEMBL5075172

SCHEMBL5075172

CCOCC(C)(C)CO[Si](C)(C)Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.32
TP53 P04637 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
SQLE Q14534 1/20 0.31
AKT1 P31749 1/20 0.31
SLC6A2 P23975 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
TSHR P16473 3/20 0.31
HPGD P15428 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085401 0.90 TAAR1 (0.36) ALDH1A1SMN1; SMN2TP53NR1H2NR1H3
SCHEMBL5075216 0.88 MAPT (0.32) ALDH1A1NR1H2NR1H3SQLE
SCHEMBL5075249 0.85 RAB9A (0.36) ALDH1A1SMN1; SMN2SLC6A2TSHR
SCHEMBL5078173 0.84 NUDT1 (0.33) ALDH1A1NR1H2NR1H3SQLESLC6A2
SCHEMBL5077300 0.82 ALDH1A1 (0.33) ALDH1A1NR1H2NR1H3SLC6A2TAAR1
SCHEMBL5078722 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5080794 0.78 MAPK1 (0.31) ALDH1A1
SCHEMBL109170 0.77 TP53 (0.42) ALDH1A1SMN1; SMN2TP53NR1H2NR1H3
SCHEMBL5081469 0.76 DUT (0.33) ALDH1A1
SCHEMBL27959438 0.75 NR1H2 (0.41) ALDH1A1TP53NR1H2NR1H3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed