Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078344 | 0.94 | NPC1 (0.33) | NPC1RAB9AMAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL5078398 | 0.92 | ALDH1A1 (0.33) | NPC1RAB9AMAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL5080791 | 0.90 | NPC1 (0.32) | NPC1RAB9AMAPK1SMN1; SMN2SIGMAR1 | |
| SCHEMBL5081838 | 0.84 | SIGMAR1 (0.33) | SMN1; SMN2SIGMAR1AOC3LMNA | |
| SCHEMBL5081735 | 0.83 | TAAR1 (0.36) | NPC1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL5077729 | 0.79 | TAAR1 (0.30) | SIGMAR1 | |
| SCHEMBL5085393 | 0.79 | TDP1 (0.38) | NPC1RAB9AMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL8430157 | 0.79 | POLB (0.39) | NPC1RAB9AMAPK1KMT2AMEN1 | |
| SCHEMBL5075137 | 0.78 | L3MBTL1 (0.34) | NPC1RAB9ASMN1; SMN2LMNAHPGD | |
| SCHEMBL5078722 | 0.77 | ALDH1A1 (0.31) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323431-B2 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-01-29 | — | — | US | claimed |
| US-20060142146-A1 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION | 2006-06-29 | — | — | US | claimed |
| US-7323431-B2 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-01-29 | — | — | US | disclosed |
| US-20060142146-A1 | Catalyst for olefin polymerization and use of the same | CHINA PETROLEUM & CHEMICAL CORPORATION | 2006-06-29 | — | — | US | disclosed |