SCHEMBL5079347

SCHEMBL5079347

Cc1cc(Oc2ccccc2)c(O)c(Oc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
MPI P34949 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48
TTR P02766 3/20 0.46
LTA4H P09960 2/20 0.45
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
CAMK2A Q9UQM7 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093898 0.83 LTA4H (0.55) KDM4EKMT2ATTRLTA4HNR1H2
SCHEMBL9326486 0.80 AR (0.48) ALDH1A1GAAKDM4EPOLBTTR
SCHEMBL4819119 0.79 TTR (0.42) ALDH1A1KDM4EPOLBTTRLTA4H
SCHEMBL9763943 0.79 RIPK1 (0.43) ALDH1A1KDM4ERECQLTTRLTA4H
SCHEMBL2916124 0.78 LTA4H (0.52) ALDH1A1GAAKMT2ATTRLTA4H
SCHEMBL9488025 0.78 LTA4H (0.42) ALDH1A1GAAKDM4EKMT2ATTR
SCHEMBL9764133 0.78 TTR (0.53) POLBTTRLTA4HNR1H2BAX
SCHEMBL9858247 0.77 TTR (0.45) TTRLTA4HNR1H2BAXTSHR
SCHEMBL13799708 0.77 TTR (0.47) ALDH1A1GAATTRLTA4HTSHR
SCHEMBL7006874 0.76 TTR (0.61) ALDH1A1GAAKDM4ETTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080125531-A1 Polymerizable Composition, Thermoplastic Resin Composition, Crosslinked Resin, And Crosslinked Resin Composite Materials ZEON COROPRATION (JP) 2008-05-29 US disclosed
EP-1589054-A1 POLYMERIZABLE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIALS Zeon Corporation (JP) 2005-10-26 EP disclosed