Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355313 | 1.00 | TTR (0.61) | TTRARKDM4EHSD17B10TRPA1 | |
| SCHEMBL16309243 | 0.88 | AR (0.54) | TTRARTRPA1ALDH1A1 | |
| SCHEMBL15463289 | 0.87 | ALDH1A1 (0.54) | TTRARTRPA1ALDH1A1GAA | |
| SCHEMBL9326486 | 0.85 | AR (0.48) | TTRARKDM4EHSD17B10TRPA1 | |
| SCHEMBL10292484 | 0.83 | TRPA1 (0.56) | TTRARKDM4EHSD17B10TRPA1 | |
| SCHEMBL7546534 | 0.82 | CA1 (0.48) | TTRARTRPA1GAA | |
| SCHEMBL13799708 | 0.82 | TTR (0.47) | TTRARALDH1A1GAA | |
| SCHEMBL5607469 | 0.81 | TEAD4 (0.57) | ARHSD17B10TRPA1ALDH1A1 | |
| SCHEMBL12386586 | 0.81 | AR (0.49) | TTRARKDM4EALDH1A1 | |
| SCHEMBL8484975 | 0.80 | NTRK1 (0.48) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160376235-A1 | Pyridone FabI Inhibitors and Uses Thereof | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2016-12-29 | — | — | US | disclosed |
| US-20080199414-A1 | COSMETIC FORMULATION COMPRISING FLAVONOID DERIVATIVES | WIRTH CORINNA | 2008-08-21 | — | — | US | disclosed |
| US-20080199414-A1 | COSMETIC FORMULATION COMPRISING FLAVONOID DERIVATIVES | WIRTH CORINNA | 2008-08-21 | — | — | US | disclosed |
| EP-1268502-A1 | O-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074834-A1 | O-ARYL GLUCOSIDE SGLT2 INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160376235-A1 | Pyridone FabI Inhibitors and Uses Thereof | PLPBP, PDXK, FBP1 | TTR 984/4885AR 4730/4885KDM4E 2013/4885 |
| US-20080199414-A1 | COSMETIC FORMULATION COMPRISING FLAVONOID DERIVATIVES | TYR, MITF, TEAD3 | TTR 2330/4885AR 3838/4885KDM4E 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.