SCHEMBL9326486

SCHEMBL9326486

Cc1ccc(O)c(Oc2ccccc2)c1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.48
TTR P02766 2/20 0.47
KDM4E B2RXH2 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TRPA1 O75762 1/20 0.45
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
FTO Q9C0B1 1/20 0.43
POLB P06746 1/20 0.43
LTA4H P09960 1/20 0.42
NR1H2 P55055 1/20 0.42
BAX Q07812 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8515094 0.88 AR (0.54) ARHSD17B10TRPA1TP53TDP1
SCHEMBL29355313 0.85 TTR (0.61) ARTTRKDM4EHSD17B10TRPA1
SCHEMBL7006874 0.85 TTR (0.61) ARTTRKDM4EHSD17B10TRPA1
SCHEMBL6902550 0.83 TRPA1 (0.56) ARKDM4EHSD17B10TRPA1TP53
SCHEMBL13799708 0.82 TTR (0.47) ARTTRTDP1ALDH1A1GAA
SCHEMBL15011327 0.81 HTT (0.51) ARTTRALDH1A1
SCHEMBL5079347 0.80 ALDH1A1 (0.48) TTRKDM4EALDH1A1GAAPOLB
SCHEMBL5380053 0.80 THRA (0.56) TTRKDM4EHSD17B10THRATHRB
SCHEMBL8484975 0.80 NTRK1 (0.48) ALDH1A1GAALTA4H
SCHEMBL822665 0.80 TSHR (0.50) TDP1ALDH1A1GAALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112320766-B Preparation method and application of hollow mesoporous inorganic oxide nanosphere solid alkali 西南大学 2023-10-27 CN disclosed
CN-112320766-A Preparation method and application of hollow mesoporous inorganic oxide nanosphere solid base 西南大学 2021-02-05 CN disclosed
US-9366906-B2 Photoreactive compounds ROLIC AG (CH) 2016-06-14 US disclosed
US-20140192305-A1 PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2014-07-10 US disclosed
US-20070054884-A1 4-SUBSTITUTED 2-ARYLOXYPHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. 2007-03-08 US disclosed
US-20070054884-A1 4-SUBSTITUTED 2-ARYLOXYPHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. 2007-03-08 US disclosed
EP-0393513-B1 Preparation of a difluorohalomethoxybenzene MITSUI TOATSU CHEMICALS (JP) 1994-03-09 EP disclosed
US-5105021-A Reacting metal phenolate with (di)bromo(chloro)difluoromethane in presence of promoter MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-04-14 US disclosed
EP-0393513-A1 Preparation of a difluorohalomethoxybenzene MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140192305-A1 PHOTOREACTIVE COMPOUNDS PCNA, CRY1, CRY2 AR 3525/4885TTR 810/4885KDM4E 3526/4885
US-20070054884-A1 4-SUBSTITUTED 2-ARYLOXYPHENOL DERIVATIVES AS ANTIBACTERIAL AGENTS CLPP, TYR, MRPL21 AR 1055/4885TTR 2906/4885KDM4E 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.