Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | BAX | Q07812 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621022 | 0.91 | TTR (0.53) | TTRPOLBSRD5A2IDH1 | |
| SCHEMBL9858253 | 0.85 | TTR (0.50) | TTRPOLBLTA4HCAMK2ANR1H2 | |
| SCHEMBL10984819 | 0.82 | POLB (0.48) | TTRPOLBLTA4H | |
| SCHEMBL2093898 | 0.81 | LTA4H (0.55) | TTRLTA4HCAMK2ANR1H2BAX | |
| SCHEMBL2914383 | 0.80 | TTR (0.50) | TTRPOLBLTA4HCAMK2A | |
| SCHEMBL5079347 | 0.78 | ALDH1A1 (0.48) | TTRPOLBLTA4HCAMK2ANR1H2 | |
| SCHEMBL2916124 | 0.76 | LTA4H (0.52) | TTRLTA4HNR1H2BAXTSHR | |
| SCHEMBL9858247 | 0.76 | TTR (0.45) | TTRLTA4HCAMK2ANR1H2BAX | |
| SCHEMBL29353999 | 0.76 | TTR (0.72) | TTRSRD5A2IDH1 | |
| SCHEMBL20679778 | 0.74 | KDM4E (0.65) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981897-A | OPTICAL PROPERTIES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-01 | — | — | US | disclosed |