Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725910 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL23829753 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL186656 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL20236440 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL4886683 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL27762779 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL27976770 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL9319315 | 0.72 | P4HA1 (0.55) | ALDH1A1HSD17B10P4HA1P4HTMHCAR2 | |
| SCHEMBL10837168 | 0.72 | HCAR3 (0.51) | ALDH1A1HSD17B10KDM4EALOX15P4HA1 | |
| SCHEMBL15737161 | 0.71 | NR4A2 (0.49) | P4HA1P4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | ALDH1A1 3032/4885HSD17B10 2203/4885KDM4E 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.