SCHEMBL507981

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL508453	0.89	PGR (0.44)	PGRKCNH2TBXAS1PPARGFNTA
	SCHEMBL12133565	0.89	PGR (0.35)	PGRFNTAFNTBPGGT1B
	SCHEMBL2716851	0.89	KCNH2 (0.49)	PGRKCNH2
	SCHEMBL508358	0.88	PGR (0.45)	PGRKCNH2TBXAS1FNTAFNTB
	SCHEMBL509725	0.85	KCNH2 (0.44)	PGRKCNH2PRMT5WDR77
	SCHEMBL509344	0.85	KCNH2 (0.41)	PGRKCNH2TBXAS1PPARGMAP4K4
	SCHEMBL509117	0.84	KCNH2 (0.53)	PGRKCNH2
	SCHEMBL509240	0.84	PGR (0.47)	PGRKCNH2SYKGRIA2GRIA4
	SCHEMBL2718123	0.83	KCNH2 (0.54)	PGRKCNH2
	SCHEMBL4818364	0.83	KCNH2 (0.42)	PGRKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.