Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | ECE1 | P42892 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.55 |
| ▸ | ITGAL | P20701 | 3/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170877 | 0.90 | KDM4E (0.69) | ALOX15KDM4EMAPTAPAF1POLB | |
| SCHEMBL170878 | 0.90 | KDM4E (0.69) | ALOX15KDM4EMAPTAPAF1POLB | |
| SCHEMBL991035 | 0.89 | KDM4E (0.68) | ALOX15KDM4EMAPTAPAF1POLB | |
| Water SCHEMBL5384991 | 0.89 | KDM4E (0.68) | ALOX15KDM4EMAPTAPAF1POLB | |
| SCHEMBL991039 | 0.89 | KDM4E (0.68) | ALOX15KDM4EMAPTAPAF1POLB | |
| Water SCHEMBL5384989 | 0.89 | KDM4E (0.68) | ALOX15KDM4EMAPTAPAF1POLB | |
| SCHEMBL28063888 | 0.85 | ALOX15 (0.64) | ALOX15POLBACEITGB2ICAM1 | |
| Dl-Tryptophan SCHEMBL27994236 | 0.83 | KDM4E (0.80) | ALOX15KDM4EMAPTAPAF1POLB | |
| SCHEMBL3125993 | 0.82 | ALOX15 (0.54) | ALOX15KDM4EMAPTAPAF1POLB | |
| SCHEMBL31036366 | 0.82 | ALOX15 (0.66) | ALOX15POLBACEECE1ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890701-A1 | COMPOSITION FOR THE TREATMENT OF MULTIPLE SCLEROSIS | GEMAC (FR) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125930-A1 | COMPOSITION FOR THE TREATMENT OF MULTIPLE SCLEROSIS | GEMAC (FR) | 2006-11-30 | — | — | WO | disclosed |