SCHEMBL5081701

SCHEMBL5081701

O=C(Oc1ccccc1)c1ccc(CO)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.56
LTA4H P09960 1/20 0.55
PRSS1 P07477 2/20 0.54
TMPRSS15 P98073 2/20 0.54
ACR P10323 1/20 0.54
NSD2 O96028 1/20 0.51
MAPT P10636 6/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TSHR P16473 2/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
ALDH1A1 P00352 5/20 0.49
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PKM P14618 1/20 0.49
GAA P10253 1/20 0.47
TMPRSS2 O15393 1/20 0.47
KLK1 P06870 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1546405 0.93 PARP10 (0.61) PARP10LTA4HNSD2MAPTSMN1; SMN2
SCHEMBL8961201 0.90 HSD17B10 (0.53) PARP10LTA4HPRSS1MAPTSMN1; SMN2
SCHEMBL28646241 0.90 HSD17B10 (0.53) PARP10LTA4HPRSS1MAPTSMN1; SMN2
SCHEMBL14139256 0.87 RXRA (0.50) PARP10PRSS1SMN1; SMN2TSHRKMT2A
SCHEMBL70034 0.86 PARP10 (0.70) PARP10PRSS1TMPRSS15ACRNSD2
SCHEMBL5706102 0.85 RAB9A (0.57) PARP10PRSS1TMPRSS15ACRNSD2
SCHEMBL26038913 0.85 PARP10 (0.56) PARP10PRSS1TMPRSS15ACRNSD2
SCHEMBL27650063 0.84 PRSS1 (0.63) PARP10PRSS1TMPRSS15ACRNSD2
SCHEMBL21389668 0.84 MEN1 (0.55) PARP10PRSS1MAPTSMN1; SMN2TSHR
SCHEMBL8983809 0.84 CES2 (0.59) PARP10PRSS1TMPRSS15ACRNSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667214-A Nanoparticles comprising drug dimers and uses thereof 南韩商帝拉贝斯特股份有限公司 2023-01-31 CN claimed
EP-3049386-B9 COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES UNIV KOELN (DE) 2020-11-18 EP claimed
EP-3049386-B1 COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES UNIV KOELN (DE) 2020-07-22 EP claimed
EP-3049386-A1 COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES Universität zu Köln (DE) 2016-08-03 EP claimed
WO-2015044177-A1 COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES UNIVERSITÄT ZU KÖLN (DE) 2015-04-02 WO claimed
EP-1753788-B1 GRAFTED FLUOROELASTOMERS DUPONT PERFORMANCE ELASTOMERS (US) 2008-07-16 EP claimed
US-7342074-B2 Grafted fluoroelastomers DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2008-03-11 US claimed
US-20070244251-A1 Grafted fluoroelastomers THE CHEMOURS COMPANY FC, LLC 2007-10-18 US claimed
US-7253236-B2 Mixing in the bulk i) a polyhydroxy curable fluoroelastomer gum with ii) a monophenol having a pendant group, iii) an accelerator and iv) an acid acceptor; heating to produce a grafted fluoroelastomer having a plurality of pendant groups bonded to carbon atoms DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2007-08-07 US claimed
EP-1753788-A1 GRAFTED FLUOROELASTOMERS DuPont Performance Elastomers L.L.C. (US) 2007-02-21 EP claimed
WO-2005123786-A1 GRAFTED FLUOROELASTOMERS DUPONT PERFORMANCE ELASTOMERS L.L.C. (US) 2005-12-29 WO claimed
US-20050277740-A1 Grafted fluoroelastomers THE CHEMOURS COMPANY FC, LLC 2005-12-15 US claimed
CN-117700468-B Preparation method of nucleotide analogue 深圳赛陆医疗科技有限公司 2024-05-03 CN disclosed
CN-117700468-A Preparation method of nucleotide analogue 深圳赛陆医疗科技有限公司 2024-03-15 CN disclosed
CN-115667214-A Nanoparticles comprising drug dimers and uses thereof 南韩商帝拉贝斯特股份有限公司 2023-01-31 CN disclosed
CN-105131298-B Silicyl polymerize benzoic acid ester compounds, purposes and combinations thereof 因特基马有限公司 2019-11-08 CN disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed
US-5395886-A Modified fluorohydrocarbon polymers DOW CORNING CORPORATION (US) 1995-03-07 US disclosed
US-5367023-A Modified fluorohydrocarbon polymers DOW CORNING CORPORATION (US) 1994-11-22 US disclosed
EP-0507468-A2 Modified fluorohydrocarbon polymers DOW CORNING CORPORATION (US) 1992-10-07 EP disclosed