Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082682 | 1.00 | MAOB (0.51) | MAOBBCHENR4A1NR4A2NR4A3 | |
| SCHEMBL5082286 | 0.95 | MAOB (0.56) | MAOBBCHENR4A1NR4A2NR4A3 | |
| SCHEMBL5076500 | 0.95 | MAOB (0.56) | MAOBBCHENR4A1NR4A2NR4A3 | |
| SCHEMBL5082780 | 0.95 | BCHE (0.54) | MAOBBCHEADAMTS4NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5079981 | 0.94 | MAOB (0.55) | MAOBBCHENR4A1NR4A2NR4A3 | |
| Bromide SCHEMBL5078347 | 0.94 | MAOB (0.55) | MAOBBCHENR4A1NR4A2NR4A3 | |
| Oxalic Acid SCHEMBL5082796 | 0.93 | MAOB (0.53) | MAOBBCHENR4A1NR4A2NR4A3 | |
| SCHEMBL5082302 | 0.90 | BCHE (0.58) | MAOBBCHENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6212620 | 0.88 | SIGMAR1 (0.57) | MAOBBCHENR4A1NR4A2NR4A3 | |
| SCHEMBL5079098 | 0.87 | NPC1 (0.43) | MMP13NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408084-B2 | Process for producing optically active β-amino alcohol | KANEKA CORPORATION (JP) | 2008-08-05 | — | — | US | disclosed |
| US-20050277791-A1 | Process for producing optically active beta-amino alcohol | KANEKA CORPORATION (JP) | 2005-12-15 | — | — | US | disclosed |
| EP-1512677-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE s-AMINO ALCOHOL | KANEKA CORPORATION (JP) | 2005-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277791-A1 | Process for producing optically active beta-amino alcohol | ADH1A, ALDH7A1, ADH1C | MAOB 404/4885BCHE 550/4885NR4A1 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.