Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083187 | 0.99 | CNR2 (0.30) | — | |
| SCHEMBL5083208 | 0.74 | KCNN4 (0.31) | — | |
| SCHEMBL4721568 | 0.72 | PDE5A (0.41) | — | |
| SCHEMBL5083191 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL8748687 | 0.71 | PPARG (0.36) | PPARG | |
| SCHEMBL8749096 | 0.68 | PDE5A (0.34) | PPARG | |
| SCHEMBL5087245 | 0.64 | CYP1A2 (0.35) | — | |
| SCHEMBL7249588 | 0.64 | CYP1A2 (0.39) | PPARG | |
| SCHEMBL7541880 | 0.62 | SIGMAR1 (0.33) | PPARG | |
| SCHEMBL21075852 | 0.61 | LTA4H (0.43) | PPARGHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375081-B2 | Therapeutic combination of a pneumocandin derivative and an antifungal agent | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | claimed |
| US-6875740-B1 | Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-04-05 | — | — | US | claimed |