SCHEMBL5083187

SCHEMBL5083187

CCCCCC(OC)Oc1ccccc1-c1[c]nns1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5083175 0.99 PPARG (0.31)
SCHEMBL5081002 0.87
SCHEMBL5083208 0.75 KCNN4 (0.31)
SCHEMBL5087247 0.74 ADRA2A (0.30)
SCHEMBL4721568 0.73 PDE5A (0.41)
SCHEMBL5083191 0.70 KDM4E (0.41) CNR2
SCHEMBL8748687 0.70 PPARG (0.36)
SCHEMBL8749096 0.69 PDE5A (0.34)
SCHEMBL5087245 0.65 CYP1A2 (0.35) CNR2
SCHEMBL7541880 0.63 SIGMAR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7375081-B2 Therapeutic combination of a pneumocandin derivative and an antifungal agent ASTELLAS PHARMA INC. (JP) 2008-05-20 US claimed
US-6875740-B1 Combination of a cyclic hexapeptide with antifungal drugs for treatment of fungal pathogens FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2005-04-05 US claimed