Styrene

Styrene

SCHEMBL5083801

C=Cc1ccccc1.CC(=O)C(=C1CCCC1)c1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
AKT1 P31749 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
AKR1C3 P42330 1/20 0.35
GLA P06280 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KMT2A Q03164 2/20 0.35
RECQL P46063 2/20 0.34
AKR1C1 Q04828 1/20 0.34
PLIN1 O60240 1/20 0.34
LMNA P02545 1/20 0.34
BCHE P06276 1/20 0.34
MAPT P10636 1/20 0.34
TNFRSF1A P19438 1/20 0.34
ACHE P22303 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7644357 0.86 ALDH1A1 (0.44) ALDH1A1TSHRAKT1TAS1R3TAS1R1
Cinnamic Alcohol SCHEMBL4435956 0.80 PAM (0.41) ALDH1A1CES2CES1GLATDP1
Styrene SCHEMBL3675467 0.78 ALDH1A1 (0.48) ALDH1A1TSHRAKT1TAS1R3TAS1R1
Styrene SCHEMBL6697336 0.76 ALDH1A1 (0.67) ALDH1A1TSHRCES2CES1AKT1
SCHEMBL8148544 0.76 AKT1 (0.47) ALDH1A1TSHRCES2CES1AKT1
Styrene SCHEMBL23406215 0.75 CES2 (0.69) ALDH1A1TSHRCES2CES1AKT1
Acetophenone SCHEMBL9718967 0.75 ALDH1A1 (0.58) ALDH1A1TSHRCES2CES1AKT1
Styrene SCHEMBL5858997 0.74 ALDH1A1 (0.70) ALDH1A1TSHRAKT1AKR1C3GLA
Styrene SCHEMBL10614939 0.74 ALDH1A1 (0.70) ALDH1A1TSHRAKT1AKR1C3GLA
Styrene SCHEMBL385100 0.74 ALDH1A1 (0.70) ALDH1A1TSHRAKT1AKR1C3GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1711558-B1 SYNDIOTATIC POLYPROPYLENE COMPOSITION COMPRISING A THERMOPLASTIC ELASTOMER RENOLIT AG (DE) 2008-06-11 EP disclosed
EP-0788338-B2 SELF-ADHERING ABSORBENT ARTICLE KIMBERLY CLARK CO (US) 2006-06-28 EP disclosed