SCHEMBL508411

SCHEMBL508411

C=CC1=NC2(CCCCC2)C(=O)O1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9864935 1.00 ALDH1A1 (0.35) ALDH1A1CYP3A4TSHRSMN1; SMN2POLB
SCHEMBL3327615 0.98 ALDH1A1 (0.36) ALDH1A1CYP3A4
SCHEMBL9823621 0.71 APP (0.38)
SCHEMBL9863514 0.71 ALDH1A1 (0.36) ALDH1A1CYP3A4
SCHEMBL9863313 0.71
SCHEMBL1840107 0.70 MAPT (0.38) ALDH1A1CYP3A4SMN1; SMN2POLB
SCHEMBL1840106 0.70 MAPT (0.38) ALDH1A1CYP3A4SMN1; SMN2POLB
SCHEMBL19790037 0.69 ALDH1A1 (0.37) ALDH1A1CYP3A4
SCHEMBL508492 0.68 ALDH1A1 (0.33) ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL1838547 0.67 ALDH1A1 (0.35) ALDH1A1CYP3A4TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP claimed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
US-11833771-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2023-12-05 US claimed
US-11825845-B2 Slippery liquid-infused porous surfaces that release hydrophilic and hydrophobic agents WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-11-28 US claimed
US-11807778-B2 Influence of partial side chain hydrolysis on the growth and morphology of reactive polymer multilayers fabricated using azlactone-functionalized polymers WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-11-07 US claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-4158392-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-04-05 EP claimed
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses ALCON INC. (CH) 2023-02-21 US claimed
WO-2022189941-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-09-15 WO claimed
EP-0367583-B1 FLUORINATED, ACRYLAMIDE-FUNCTIONAL MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-04 EP claimed
US-5075352-A Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-24 US claimed
US-5013795-A Azlactone graft copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-07 US claimed
EP-0413551-A2 Stabilized polymeric dispersions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-20 EP claimed
EP-0367583-A2 Fluorinated, acrylamide-functional monomers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-09 EP claimed
EP-0336762-A2 Process for acrylamidoacylation of alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-11 EP claimed
EP-0128731-B1 AZLACTONE-CONTAINING PRESSURE-SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-09-16 EP claimed
US-4619867-A WITH ACRYLIC-FUNCTIONAL CARBOXYLIC ACID, AND ACRYLIC MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-10-28 US claimed
US-4451619-A COPOLYMERIZING AN ALKENYLAZLACTONE, RING OPENING WITH NUCLEOPHILE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-05-29 US claimed
EP-0105666-A1 Method of hydrophilizing or hydrophobizing polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584097-B2 Method for making opaque colored silicone hydrogel contact lenses COIL, CRYAB, CRYAA ALDH1A1 3383/4885CYP3A4 1161/4885TSHR 3017/4885
US-11825845-B2 Slippery liquid-infused porous surfaces that release hydrophilic and hydrophobic agents CLPP, MSN, LIPA ALDH1A1 1712/4885CYP3A4 1937/4885TSHR 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.