Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL5077806 | 0.97 | NAAA (0.39) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL721510 | 0.97 | NAAA (0.39) | NAAAEPHX1TSHRHTR2CCES2 | |
| Potassium Ion SCHEMBL5028598 | 0.90 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL11051162 | 0.88 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL18010665 | 0.88 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL3329233 | 0.88 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL198244 | 0.88 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL9814071 | 0.88 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| SCHEMBL18527025 | 0.88 | NAAA (0.38) | NAAAEPHX1TSHRHTR2CCES2 | |
| Potassium Ion SCHEMBL10867242 | 0.86 | TSHR (0.35) | NAAAEPHX1TSHRHTR2CCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345112-B2 | Thermoplastic resin composition and method for preparing thereof | LG CHEM, LTD. (KR) | 2008-03-18 | — | — | US | disclosed |
| US-20060106163-A1 | Thermoplastic resin composition and method for preparing thereof | LG CHEM, LTD. (KR) | 2006-05-18 | — | — | US | disclosed |