Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL3852404 | 0.97 | TSHR (0.33) | TSHRMAPK1MEN1KMT2APPARD | |
| Phosphoric Acid SCHEMBL8181905 | 0.95 | TSHR (0.32) | TSHRMAPK1MEN1KMT2APPARD | |
| SCHEMBL29183872 | 0.86 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| SCHEMBL30539 | 0.83 | TSHR (0.44) | TSHRMAPK1MEN1KMT2A | |
| Fluoride SCHEMBL923685 | 0.80 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL5393633 | 0.80 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Water SCHEMBL1246621 | 0.80 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Iodide SCHEMBL5874477 | 0.80 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Methane SCHEMBL1001960 | 0.80 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Bromide SCHEMBL5874693 | 0.80 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080245262-A1 | Layered silicate of attapulgite or bentonite and a hydroxyalkyl ammonium salt of an aluminum phosphate; paints | ASHLAND-SUDCHEMIE-KERNFEST GMBH (DE) | 2008-10-09 | — | — | US | disclosed |