Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8181905 | 0.97 | TSHR (0.32) | TSHRMAPK1MEN1KMT2APPARD | |
| Phosphoric Acid SCHEMBL5084492 | 0.97 | TSHR (0.32) | TSHRMAPK1MEN1KMT2APPARD | |
| SCHEMBL30539 | 0.85 | TSHR (0.44) | TSHRMAPK1MEN1KMT2A | |
| Fluoride SCHEMBL923685 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Iodide SCHEMBL5874477 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Methane SCHEMBL1001960 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Water SCHEMBL1246621 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Bromide SCHEMBL5874693 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL5393633 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL634629 | 0.82 | TSHR (0.41) | TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939521-B2 | Reuse of hypersaline brine with ionic liquids | SAUDI ARABIAN OIL COMPANY (SA) | 2024-03-26 | — | — | US | disclosed |
| US-20240059958-A1 | REUSE OF HYPERSALINE BRINE WITH IONIC LIQUIDS | SAUDI ARABIAN OIL COMPANY (SA) | 2024-02-22 | — | — | US | disclosed |
| WO-2024039814-A1 | REUSE OF HYPERSALINE BRINE WITH IONIC LIQUIDS | SAUDI ARABIAN OIL COMPANY (SA) | 2024-02-22 | — | — | WO | disclosed |
| US-20140348959-A1 | Formulations and Methods for Treating Ear Conditions | PARTICLE SCIENCES, INC. | 2014-11-27 | — | — | US | disclosed |
| WO-2013123249-A2 | FORMULATIONS AND METHODS FOR TREATING EAR CONDITIONS | PARTICLE SCIENCES, INC. (US) | 2013-08-22 | — | — | WO | disclosed |
| EP-1928439-A4 | METHODS FOR TREATMENT AND PREVENTION OF OTITIS MEDIA USING CHEMICAL PENETRATION ENHANCERS TO FACILITATE TRANSMEMBRANE DRUG DELIVERY INTO THE MIDDLE EAR | PIEDMONT PHARMACEUTICALS LLC (US) | 2009-04-29 | — | — | EP | disclosed |
| US-20080318918-A1 | Methods for Treatment and Prevention of Otitis Media Using Nonionic Surfactants to Facilitate Transmembrane Drug Delivery into the Middle Ear | PIEDMONT PHARMACEUTICALS LLC | 2008-12-25 | — | — | US | disclosed |
| US-20080269187-A1 | Methods for Treatment and Prevention of Otitis Media Using Chemical Penetration Enhancers to Facilitate Transmembrane Drug Delivery Into the Middle Ear | PIEDMONT PHARMACEUTICALS LLC | 2008-10-30 | — | — | US | disclosed |
| CN-101272807-A | Methods for treatment and prevention of otitis media using nonionic surfactants to facilitate transmembrane drug delivery to the middle ear | PIEDMONT PHARMACEUTICALS LLC (US) | 2008-09-24 | — | — | CN | disclosed |
| EP-1784164-A4 | METHODS FOR TRANSMEMBRANE TREATMENT AND PREVENTION OF OTITIS MEDIA | PIEDMONT PHARMACEUTICALS LLC (US) | 2008-07-09 | — | — | EP | disclosed |
| US-20070218050-A1 | Methods for treatment and prevention of otitis media using chemical penetration enhancers to facilitate transmembrane drug delivery into the middle ear | PIEDMONT PHARMACEUTICALS LLC | 2007-09-20 | — | — | US | disclosed |
| EP-1784164-A2 | METHODS FOR TRANSMEMBRANE TREATMENT AND PREVENTION OF OTITIS MEDIA | Piedmont Pharmaceuticals, LLC (US) | 2007-05-16 | — | — | EP | disclosed |
| WO-2007037874-A2 | METHODS FOR TREATMENT AND PREVENTION OF OTITIS MEDIA USING CHEMICAL PENETRATION ENHANCERS TO FACILITATE TRANSMEMBRANE DRUG DELIVERY INTO THE MIDDLE EAR | PIEDMONT PHARMACEUTICALS LLC (US) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007037886-A2 | METHODS FOR TREATMENT AND PREVENTION OF OTITIS MEDIA USING NONIONIC SURFACTANTS TO FACILITATE TRANSMEMBRANE DRUG DELIVERY INTO THE MIDDLE EAR | PIEDMONT PHARMACEUTICALS LLC (US) | 2007-04-05 | — | — | WO | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| WO-2006029074-A2 | METHODS FOR TRANSMEMBRANE TREATMENT AND PREVENTION OF OTITIS MEDIA | PIEDMONT PHARMACEUTICALS, LLC (US) | 2006-03-16 | — | — | WO | disclosed |
| CN-1674870-A | Liposomes containing biologically active compounds | PIEDMONT PHARMACEUTICALS LLC (US) | 2005-09-28 | — | — | CN | disclosed |
| US-20030235610-A1 | Liposomes containing biologically active compounds | PIEDMONT PHARMACEUTICALS, LLC | 2003-12-25 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4250046-A | POLYOXYALKYLENE GLYCOL | PENNWALT CORPORATION (US) | 1981-02-10 | — | — | US | disclosed |