SCHEMBL5085201

SCHEMBL5085201

CS(=O)(=O)c1ccc2c(c1)ncn2Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 14/20 0.61
TNF P01375 1/20 0.57
CYP11B1 P15538 1/20 0.57
CYP11B2 P19099 1/20 0.57
C1S P09871 1/20 0.54
GHSR Q92847 1/20 0.53
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13508799 0.88 KCNH2 (0.59) NR1I2CYP11B1CYP11B2GHSR
SCHEMBL22533660 0.84 GHSR (0.52) NR1I2CYP11B1CYP11B2C1SGHSR
SCHEMBL8874396 0.81 ALDH1A1 (0.59) NR1I2GHSRKMT2A
SCHEMBL15345067 0.79 CYP11B1 (0.68) NR1I2TNFCYP11B1CYP11B2KMT2A
SCHEMBL3602016 0.78 DRD2 (0.55) KMT2A
SCHEMBL3641606 0.77 DRD2 (0.41) NR1I2C1S
SCHEMBL9680188 0.77 ALDH1A1 (0.45) NR1I2C1SGHSRKMT2A
SCHEMBL4748504 0.76 PKM (0.77) NR1I2TNFCYP11B1CYP11B2KMT2A
SCHEMBL3761479 0.76 CYP11B1 (0.66) NR1I2TNFCYP11B1CYP11B2
SCHEMBL15206007 0.76 CYP11B1 (0.66) NR1I2TNFCYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100028299-A1 Methods and compositions of treating a flaviviridae family viral infection THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-02-04 US disclosed
US-20100028299-A1 Methods and compositions of treating a flaviviridae family viral infection THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-02-04 US disclosed
EP-1211555-B1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJIFILM CORP (JP) 2008-12-31 EP disclosed
US-6875562-B2 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 2005-04-05 US disclosed
US-20030215760-A1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. 2003-11-20 US disclosed
US-6537742-B2 Photosensitivity; light absorption strength; latent imaging FUJI PHOTO FILM CO., LTD. (JP) 2003-03-25 US disclosed
EP-0838719-B1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 2003-02-12 EP disclosed
US-20020150848-A1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. 2002-10-17 US disclosed
EP-1211555-A2 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 2002-06-05 EP disclosed
US-6387610-B1 SILVER HALIDE EMULSION SPECTRA SENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 2002-05-14 US disclosed
US-5449596-A Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-12 US disclosed
US-5387483-A Developer containing silver halide solvent and hydroquinone; has pH up to 11.8 FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed
EP-0618492-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-10-05 EP disclosed
EP-0608777-A1 Processing of lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-08-03 EP disclosed
EP-0601600-A2 Processing of lithographic printing material and developer used therein FUJI PHOTO FILM CO., LTD. (JP) 1994-06-15 EP disclosed
EP-0598241-A1 Lithographic printing material FUJI PHOTO FILM CO., LTD. (JP) 1994-05-25 EP disclosed
US-5260183-A Cyanine dye, thiocyanate, triazolopyrimidine spectral sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-09 US disclosed
US-5035984-A Computer output images, nucleating agent FUJI PHOTO FILM CO., LTD. (JP) 1991-07-30 US disclosed
US-5015561-A Method for forming a direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1991-05-14 US disclosed
EP-0331185-A2 Silver halide photographic element for forming direct positive images and a method for forming said images FUJI PHOTO FILM CO., LTD. (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028299-A1 Methods and compositions of treating a flaviviridae family viral infection EIF2AK2, NSUN3, NSUN2 NR1I2 2181/4885TNF 2956/4885CYP11B1 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.