Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14407542 | 0.81 | NR1I2 (0.52) | GSK3BMAPTNR1I2MAOAMAOB | |
| SCHEMBL5085228 | 0.81 | NR1I2 (0.63) | GSK3BMAPTNR1I2MAOAMAOB | |
| SCHEMBL20716157 | 0.80 | NQO1 (0.54) | MAOBLMNARAB9AKMT2ANPSR1 | |
| SCHEMBL13962133 | 0.79 | CA1 (0.50) | MAPTNR1I2MAOAMAOBCA1 | |
| SCHEMBL8552180 | 0.79 | LMNA (0.51) | GSK3BMAPTNR1I2MAOAMAOB | |
| SCHEMBL16795750 | 0.79 | MAPT (0.50) | GSK3BMAPTNR1I2MAOAMAOB | |
| SCHEMBL24148257 | 0.77 | MAPT (0.62) | GSK3BMAPTCES2CES1CA1 | |
| SCHEMBL16795587 | 0.77 | LMNA (0.55) | GSK3BMAPTMEN1LMNARAB9A | |
| SCHEMBL9364978 | 0.77 | CES2 (0.55) | MAOAMAOBCES2CES1MEN1 | |
| SCHEMBL202055 | 0.75 | GSK3B (1.00) | GSK3BMAPTCES2CES1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585457-B1 | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMA SPA (IT) | 2015-07-22 | — | — | EP | disclosed |
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |
| EP-2480080-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2338334-A1 | Pesticides and uses thereof | Dow AgroSciences LLC (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2011038163-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2011-03-31 | — | — | WO | disclosed |
| EP-2274307-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009120720-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES,INC. (US) | 2009-10-01 | — | — | WO | disclosed |