Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 4/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047051 | 0.81 | AKR1C4 (0.38) | GPR17AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5586405 | 0.74 | THRB (0.42) | HSD17B10CYP3A4TDP1 | |
| SCHEMBL449703 | 0.73 | THRA (0.44) | HSD17B10CYP3A4TDP1 | |
| SCHEMBL1920376 | 0.72 | FFAR1 (0.50) | — | |
| SCHEMBL1989802 | 0.70 | KDM4E (0.46) | HSD17B10TDP1GPR35 | |
| SCHEMBL22653561 | 0.70 | TDP1 (0.45) | GPR17AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7074081 | 0.69 | HSD17B10 (0.40) | HSD17B10 | |
| SCHEMBL8897387 | 0.69 | AKR1B1 (0.43) | AKR1C4AKR1C3AKR1C2AKR1C1HSD17B10 | |
| SCHEMBL10890555 | 0.68 | TET2 (0.31) | HSD17B10 | |
| SCHEMBL5266797 | 0.68 | TET2 (0.31) | HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-4224244-A1 | EYEGLASS LENS | Hoya Lens Thailand Ltd. (TH) | 2023-08-09 | — | — | EP | disclosed |
| EP-4224245-A1 | SPECTACLE LENS | Hoya Lens Thailand Ltd. (TH) | 2023-08-09 | — | — | EP | disclosed |
| US-20230176250-A1 | SPECTACLE LENS | HOYA LENS THAILAND LTD. (TH) | 2023-06-08 | — | — | US | disclosed |
| US-20230111587-A1 | SPECTACLE LENS | HOYA LENS THAILAND LTD. (TH) | 2023-04-13 | — | — | US | disclosed |
| US-20080145545-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | CITIBANK, N.A., AS COLLATERAL AGENT | 2008-06-19 | — | — | US | disclosed |