Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083436 | 0.90 | USP30 (0.45) | GPR119HDAC1USP30CHEK2SCN9A | |
| SCHEMBL4097506 | 0.87 | GPR119 (0.57) | GPR119HDAC1USP30 | |
| SCHEMBL3987206 | 0.87 | GPR119 (0.53) | GPR119HDAC1HDAC4 | |
| SCHEMBL3987089 | 0.86 | GPR119 (0.59) | GPR119 | |
| SCHEMBL3984151 | 0.85 | NPC1 (0.40) | GPR119USP30 | |
| SCHEMBL3984090 | 0.85 | CXCR4 (0.42) | USP30 | |
| SCHEMBL16466490 | 0.81 | USP30 (0.48) | GPR119USP30 | |
| SCHEMBL3984822 | 0.80 | ALDH1A1 (0.48) | GPR119USP30 | |
| SCHEMBL3984528 | 0.80 | GPR119 (0.49) | GPR119HDAC1USP30 | |
| SCHEMBL3983980 | 0.80 | USP30 (0.46) | GPR119HDAC1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103123-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103123-A1 | New compounds | GPR119, GPR139, GPR180 | GPR119 1/4885HDAC1 2847/4885HDAC4 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.