SCHEMBL509336

SCHEMBL509336

C=CC(=O)N(CC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C)CC(O)COCCC[SiH2]C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508665 0.84
SCHEMBL23493061 0.81 TSHR (0.38)
SCHEMBL508852 0.79
SCHEMBL509139 0.77 ZDHHC20 (0.35) ZDHHC20
SCHEMBL509335 0.77 ZDHHC20 (0.35) ZDHHC20
SCHEMBL15267223 0.76 ZDHHC20 (0.32) ZDHHC20
SCHEMBL30306612 0.76 USP2 (0.47)
SCHEMBL507906 0.75 ZDHHC20 (0.35) ZDHHC20
Methacrylic Acid SCHEMBL2125330 0.74 USP2 (0.38)
SCHEMBL331867 0.74 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
US-12286501-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2025-04-29 US claimed
EP-4514596-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-1716436-B1 (METH) ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM JOHNSON & JOHNSON VISION CARE (US) 2011-04-06 EP claimed
WO-2010133680-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS NOVARTIS AG (CH) 2010-11-25 WO claimed
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed
US-20100258961-A1 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2010-10-14 US claimed
WO-2010071691-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2010-06-24 WO claimed
US-20070167592-A1 (METH)ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES JOHNSON & JOHNSON VISION CARE, INC. 2007-07-19 US claimed
US-7214809-B2 (Meth)acrylamide monomers containing hydroxy and silicone functionalities JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-05-08 US claimed
EP-1716436-A1 (METH) ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM Johnson and Johnson Vision Care, Inc. (US) 2006-11-02 EP claimed
WO-2005078482-A1 (METH)ACRYLAMIDE MONOMERS CONTAINING HYDROXY AND SILICONE FUNCTIONALITIES AND POLYMERS MADE THEREFROM JOHNSON & JOHNSON VISION CARE, INC. (US) 2005-08-25 WO claimed
US-20050176911-A1 (Meth)acrylamide monomers containing hydroxy and silicone functionalities JOHNSON & JOHNSON VISION CARE, INC. 2005-08-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES CRYZ, STRA6, PHOSPHO1 ZDHHC20 3821/4885
US-20100296049-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS VCL, MACF1, CFL1 ZDHHC20 1195/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 ZDHHC20 4370/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ ZDHHC20 1842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.