SCHEMBL5087265

SCHEMBL5087265

CCC(C)N=C=NN(C)C

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.46
TRPV1 Q8NER1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626820 0.86 TRPA1 (0.33) TRPA1TRPV1
Hydrochloric Acid SCHEMBL7420163 0.85 TRPA1 (0.32) TRPA1TRPV1
SCHEMBL1883811 0.79 TRPA1 (0.60) TRPA1TRPV1
SCHEMBL6294131 0.78
SCHEMBL23598722 0.72 TRPA1 (0.52) TRPA1TRPV1
SCHEMBL9542006 0.72
SCHEMBL20203690 0.72 TRPA1 (0.52) TRPA1TRPV1
SCHEMBL287060 0.70
SCHEMBL9914203 0.69
SCHEMBL220893 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2298736-B1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INC (US) 2015-07-15 EP disclosed
EP-2295407-B1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INC (US) 2014-11-05 EP disclosed
US-7462689-B2 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK BIOSCIENCES, INC. (US) 2008-12-09 US disclosed
US-6800728-B2 CROSSLINKING AND IMMOBILIZING BIOMOLECULES, DRUGS AND SYNTHETIC POLYMERS WITH A THIOL OR AMINO REACTIVE GROUP AND HYDRAZINO OR OXYAMINO MOIETIES SOLULINK BIOSCIENCES, INC. 2004-10-05 US disclosed
EP-1315699-A2 HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS Solulink, Incorporated (US) 2003-06-04 EP disclosed
US-20030013857-A1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INCORPORATED 2003-01-16 US disclosed
WO-2001070685-A2 HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS SOLULINK, INCORPORATED (US) 2001-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030013857-A1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents HLCS, DUOX1, HAO2 TRPA1 4439/4885TRPV1 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.