Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decyltriphenylphosphonium SCHEMBL3654788 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL10684637 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL5085133 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL2505241 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL3859955 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL5091833 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL5085194 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL6904643 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL2354963 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL298493 | 0.98 | HIF1A (0.56) | HIF1ACHRNA7ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2823709-A1 | The use of ionic salts containing phosphonium cation | Akademia im. Jana Dlugosza (PL) | 2015-01-14 | — | — | EP | claimed |
| CN-110386855-B | 1-halodiene and process for preparing it and (9E, 111Z) -9, 11-hexadecadienylacetate | 信越化学工业株式会社 | 2023-03-28 | — | — | CN | disclosed |
| CN-111602087-B | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer and compound | JSR株式会社 | 2023-03-24 | — | — | CN | disclosed |
| EP-3885334-B1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | SHINETSU CHEMICAL CO (JP) | 2023-01-11 | — | — | EP | disclosed |
| US-11420919-B2 | Process for preparing a formylalkenyl alkoxymethyl ether compound and processes for preparing conjugated diene compounds from the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-08-23 | — | — | US | disclosed |
| US-20210300854-A1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-09-30 | — | — | US | disclosed |
| EP-3885334-A1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
| CN-113443971-A | Method for producing alkynylalkoxymethyl ether compound and method for producing conjugated diene compound therefrom | 信越化学工业株式会社 | 2021-09-28 | — | — | CN | disclosed |
| EP-3556742-B1 | 1-HALOALKADIENE AND PROCESS FOR PREPARING THE SAME AND A PROCESS FOR PREPARING (9E,11Z)-9,11-HEXADECADIENYL ACETATE | SHINETSU CHEMICAL CO (JP) | 2021-07-14 | — | — | EP | disclosed |
| CN-111602087-A | Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, polymer and compound | JSR株式会社 | 2020-08-28 | — | — | CN | disclosed |
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5004822-A | Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-04-02 | — | — | US | disclosed |
| US-4622337-A | INSECTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-11 | — | — | US | disclosed |
| US-4464391-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-08-07 | — | — | US | disclosed |
| US-4343731-A | Epoxy resin composition and process for production | GENERAL ELECTRIC COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| US-4320222-A | PHOSPHONIUM HALIDE CATALYSTS AND POTASSIUM HYDROXIDE OR HALIDE | SHELL OIL COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
| US-4118373-A | Preparation of urethane elastomers from epoxy resin, polyols and polyisocyanates using a catalyst composition of an organometal salt with either nitrogen or phosphorus compounds | THE DOW CHEMICAL COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4081491-A | HEAT CURABLE | SHELL OIL COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4027040-A | ANALGESICS | ROUSSEL-UCLAF (FR) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300854-A1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | ADH1C, ORC3, ADH1A | HIF1A 2926/4885CHRNA7 505/4885ALDH1A1 18/4885 |
| US-11420919-B2 | Process for preparing a formylalkenyl alkoxymethyl ether compound and processes for preparing conjugated diene compounds from the same | ADH1C, ORC3, ADH1A | HIF1A 2926/4885CHRNA7 505/4885ALDH1A1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.