Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 4/20 | 0.69 |
| ▸ | AR | P10275 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | YES1 | P07947 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3'-Hydroxyflavanone SCHEMBL5929195 | 1.00 | CYP19A1 (0.79) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| 3'-Hydroxyflavanone SCHEMBL15531909 | 1.00 | CYP19A1 (0.79) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| 3'-Hydroxyflavanone SCHEMBL29606797 | 1.00 | CYP19A1 (0.79) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| SCHEMBL21518314 | 0.90 | ADORA3 (0.76) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| SCHEMBL6848876 | 0.88 | CYP19A1 (1.00) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| SCHEMBL4362380 | 0.88 | AR (0.81) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| SCHEMBL4953726 | 0.88 | AR (0.81) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| Flavanone SCHEMBL27595693 | 0.88 | ADORA3 (0.88) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| 4'-Hydroxy-Flavanone SCHEMBL10362253 | 0.85 | ADORA3 (1.00) | CYP19A1ADORA3NPC1RAB9ACYP3A4 | |
| 4'-Hydroxy-Flavanone SCHEMBL2283830 | 0.85 | ADORA3 (1.00) | CYP19A1ADORA3NPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113322288-B | Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-12-26 | — | — | CN | claimed |
| US-20230102194-A1 | Novel Flavone Hydroxylases, Microorganism for Synthesizing Flavone C-Glycoside Compounds, and Use Thereof | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2023-03-30 | — | — | US | claimed |
| EP-4112732-A1 | NOVEL FLAVONE HYDROXYLASES, MICROORGANISM FOR SYNTHESIZING FLAVONE C-GLYCOSIDE COMPOUNDS, AND USE THEREOF | CAS Center for Excellence in Molecular Plant Sciences (CN) | 2023-01-04 | — | — | EP | claimed |
| CN-112604675-B | Preparation method and application of azobenzene dicarboxamide bridged beta-cyclodextrin chiral stationary phase | 南昌大学 | 2022-06-14 | — | — | CN | claimed |
| CN-113322288-A | Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycosides and application thereof | 中国科学院分子植物科学卓越创新中心 | 2021-08-31 | — | — | CN | claimed |
| CN-112604675-A | Preparation method and application of azobenzene dicarboxamide bridged beta-cyclodextrin chiral stationary phase | 南昌大学 | 2021-04-06 | — | — | CN | claimed |
| US-20200123673-A1 | ELECTROLYTIC TIN ALLOY PLATING SOLUTION | C. UYEMURA & CO., LTD. (JP) | 2020-04-23 | — | — | US | claimed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | claimed |
| CN-113322288-B | Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-12-26 | — | — | CN | disclosed |
| CN-116120399-A | Peony seed meal source tyrosine inhibitory peptide and preparation method thereof | 河南科技大学 | 2023-05-16 | — | — | CN | disclosed |
| US-20230102194-A1 | Novel Flavone Hydroxylases, Microorganism for Synthesizing Flavone C-Glycoside Compounds, and Use Thereof | CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) | 2023-03-30 | — | — | US | disclosed |
| EP-4112732-A1 | NOVEL FLAVONE HYDROXYLASES, MICROORGANISM FOR SYNTHESIZING FLAVONE C-GLYCOSIDE COMPOUNDS, AND USE THEREOF | CAS Center for Excellence in Molecular Plant Sciences (CN) | 2023-01-04 | — | — | EP | disclosed |
| CN-112604675-B | Preparation method and application of azobenzene dicarboxamide bridged beta-cyclodextrin chiral stationary phase | 南昌大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113262767-B | Perylene diimide-based bridged bis-beta-cyclodextrin stationary phase and preparation method and application thereof | 南昌大学 | 2022-05-20 | — | — | CN | disclosed |
| US-20060018861-A1 | Skin care composition | PROCTER & GAMBLE COMPANY, THE | 2006-01-26 | — | — | US | disclosed |
| US-20060018858-A1 | Skin care composition | THE PROCTER & GAMBLE COMPANY | 2006-01-26 | — | — | US | disclosed |
| US-20060018862-A1 | Substrate based skin care device | PROCTER & GAMBLE COMPANY, THE | 2006-01-26 | — | — | US | disclosed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060018862-A1 | Substrate based skin care device | CUTA, TYR, PROC | CYP19A1 357/4885ADORA3 4156/4885NPC1 3205/4885 |
| US-20060018858-A1 | Skin care composition | CUTA, FLNB, CYP24A1 | CYP19A1 799/4885ADORA3 1478/4885NPC1 1104/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | CYP19A1 460/4885ADORA3 4438/4885NPC1 3898/4885 |
| US-20060018861-A1 | Skin care composition | CUTA, SERPINB6, FLNB | CYP19A1 1092/4885ADORA3 1349/4885NPC1 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.