Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565107 | 0.89 | STK17B (0.38) | STK17BKMT2AALDH1A1KDM4EOXTR | |
| SCHEMBL3626959 | 0.79 | POLB (0.47) | OXTRAVPR1APOLBGAA | |
| SCHEMBL3565103 | 0.78 | POLB (0.45) | KMT2AOXTRAVPR1AMEN1POLB | |
| SCHEMBL15225861 | 0.75 | HTT (0.41) | KMT2AALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL15225860 | 0.70 | SLC6A3 (0.35) | STK17BKMT2AMAP3K8SMN1; SMN2 | |
| SCHEMBL15225858 | 0.67 | EGFR (0.35) | STK17BMAP3K8SMN1; SMN2 | |
| SCHEMBL1479076 | 0.64 | MET (0.33) | STK17BKMT2AMAP3K8MEN1GAA | |
| SCHEMBL2533961 | 0.62 | MCHR1 (0.32) | STK17BKMT2AMAP3K8 | |
| SCHEMBL6002954 | 0.61 | IKBKB (0.54) | STK17BKMT2AKDM4ELMNAMAP3K8 | |
| SCHEMBL3710058 | 0.60 | GRIN3B (0.33) | STK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904504-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | Methylgene, Inc. (CA) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007054831-A2 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE, INC. (CA) | 2007-05-18 | — | — | WO | disclosed |