SCHEMBL5089183

SCHEMBL5089183

CCc1c[c]c(C)c(-c2cc(C(F)(F)C(F)(F)F)ccc2Cl)c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CETP P11597 1/20 0.32
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4439962 0.82 MEN1 (0.34) CTSSCTSK
SCHEMBL4437901 0.79 CTSS (0.34) CTSSCTSK
SCHEMBL5089186 0.77 CETP (0.32) CETPCTSSCTSK
SCHEMBL3664036 0.77 CYP1A2 (0.35)
SCHEMBL5086382 0.71 ALDH1A1 (0.33)
SCHEMBL3664940 0.70 MCL1 (0.36) CTSSCTSK
SCHEMBL4437905 0.68 AR (0.39) CTSSCTSK
SCHEMBL4428500 0.67 CNR1 (0.32)
SCHEMBL4439963 0.66 IDO1 (0.38)
SCHEMBL4608305 0.65 RORC (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008091594-A2 FUNGICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-31 WO disclosed