SCHEMBL509079

SCHEMBL509079

C=C(CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)OC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3761052 0.86
SCHEMBL3761055 0.85
SCHEMBL17797173 0.83
SCHEMBL9938511 0.79
SCHEMBL11123306 0.75 ALOX15 (0.31)
SCHEMBL8645372 0.74
SCHEMBL403239 0.74 TBXAS1 (0.34)
SCHEMBL8501219 0.72 CHRM2 (0.39)
SCHEMBL3799645 0.70 TSHR (0.35)
SCHEMBL820150 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
US-20250223392-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC (CH) 2025-07-10 US claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
US-20240254269-A1 HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF ALCON INC. (CH) 2024-08-01 US claimed
WO-2010056687-A2 SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS NOVARTIS AG (CH) 2010-05-20 WO claimed
US-20100120939-A1 SILICONE HYDROGEL MATERIALS WITH CHEMICALLY BOUND WETTING AGENTS ALCON INC. (CH) 2010-05-13 US claimed
EP-2129513-A2 PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS Novartis Ag (CH) 2009-12-09 EP claimed
EP-2091979-A2 ACTINICALLY CURABLE SILICONE HYDROGEL COPOLYMERS AND USES THEREOF Novartis AG (CH) 2009-08-26 EP claimed
WO-2008116131-A2 PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS NOVARTIS AG (CH) 2008-09-25 WO claimed
US-20080231798-A1 Prepolymers with dangling polysiloxane-containing polymer chains ALCON INC. (CH) 2008-09-25 US claimed
WO-2008076736-A2 ACTINICALLY CURABLE SILICONE HYDROGEL COPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2008-06-26 WO claimed
US-20080143003-A1 Actinically curable silicone hydrogel copolymers and uses thereof ALCON INC. (CH) 2008-06-19 US claimed
WO-2007064594-A2 NEW COATINGS ON OPHTHALMIC LENSES BAUSCH & LOMB INCORPORATED (US) 2007-06-07 WO claimed
US-20070122540-A1 Coatings on ophthalmic lenses BAUSCH & LOMB INCORPORATED 2007-05-31 US claimed