SCHEMBL8501219

SCHEMBL8501219

C[Si](C)(C)O[Si](CCCOC(N)=O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39
CHRM5 P08912 2/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
LMNA P02545 2/20 0.39
CHRNB2 P17787 2/20 0.39
CHRNA4 P43681 2/20 0.39
HTR1A P08908 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
CHRNA7 P36544 1/20 0.39
ALOX15 P16050 1/20 0.37
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
ATM Q13315 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29112715 0.84 ATM (0.33) TSHRATM
SCHEMBL14502559 0.82 ALDH1A1 (0.48) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29112722 0.82 HCAR2 (0.32) TSHRATM
SCHEMBL8501812 0.81 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8853823 0.81 ATM (0.53) LMNATSHRATMMAPTRAB9A
SCHEMBL373897 0.81 ATM (0.53) LMNATSHRATMMAPTRAB9A
SCHEMBL113819 0.80 LMNA (0.42) CHRM2CHRM4CHRM5CHRM1CHRM3
Acrylamide SCHEMBL29899654 0.80 TSHR (0.50) TSHRATMMAPTRAB9ANPSR1
SCHEMBL16244601 0.79 LMNA (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15508763 0.79 ATM (0.31) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150011670-A1 POLYMERIZABLE AMIDO-CONTAINING ORGANOSILICON COMPOUNDS, SILICON-CONTAINING POLYMERS AND BIOMEDICAL DEVICES THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2015-01-08 US claimed
US-20260137603-A1 MULTILAYER MAKEUP PROTECTIVE COSMETIC KOSE CORPORATION (JP) 2026-05-21 US disclosed
US-12611370-B2 Microemulsion composition and cosmetic containing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-28 US disclosed
US-20260053725-A1 COSMETIC PREPARATION CONTAINING CROSSLINKED ORGANIC SILICON RESIN AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-02-26 US disclosed
US-12478565-B2 Water-dispersion emulsion composition, method for manufacturing the same, emulsion addition-cured composition, and cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-25 US disclosed
EP-4574131-A1 COSMETIC PREPARATION CONTAINING CROSSLINKED ORGANIC SILICON RESIN AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-25 EP disclosed
EP-3900700-B1 MICROEMULSION COMPOSITION, CURED PRODUCT THEREOF, AND COSMETIC MATERIAL CONTAINING SAME SHINETSU CHEMICAL CO (JP) 2023-09-13 EP disclosed
US-20230149290-A1 MICROEMULSION COMPOSITION AND COSMETIC CONTAINING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed
EP-4140543-A1 MICROEMULSION COMPOSITION AND COSMETIC CONTAINING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-03-01 EP disclosed
US-20220387265-A1 WATER-DISPERSION EMULSION COMPOSITION, METHOD FOR MANUFACTURING THE SAME, EMULSION ADDITION-CURED COMPOSITION, AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-12-08 US disclosed
EP-3479817-B1 COSMETIC SHINETSU CHEMICAL CO (JP) 2022-05-04 EP disclosed
US-20220062121-A1 MICROEMULSION COMPOSITION, CURED MATERIAL THEREOF, AND COSMETIC CONTAINING THE CURED MATERIAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-03-03 US disclosed
EP-3900700-A1 MICROEMULSION COMPOSITION, CURED PRODUCT THEREOF, AND COSMETIC MATERIAL CONTAINING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-27 EP disclosed
US-10869828-B2 Cosmetic SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-12-22 US disclosed
EP-3673894-A1 COSMETIC Shiseido Co., Ltd. (JP) 2020-07-01 EP disclosed
US-20200038302-A1 WATER-IN-OIL TYPE EMULSIFICATION COSMETIC SHISEIDO COMPANY, LTD. (JP) 2020-02-06 US disclosed
US-20190201317-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-07-04 US disclosed
EP-3479817-A1 COSMETIC Shin-Etsu Chemical Co., Ltd. (JP) 2019-05-08 EP disclosed
US-5886205-A Process for producing silicon-containing isocyanate compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-03-23 US disclosed
US-5583244-A Siloxane-containing pullulan and method for the preparation thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611370-B2 Microemulsion composition and cosmetic containing the same MGLL, SGMS2, MAN2B1 CHRM2 247/4885CHRM4 1053/4885CHRM5 738/4885
US-20230149290-A1 MICROEMULSION COMPOSITION AND COSMETIC CONTAINING THE SAME MAN2B1, MGLL, LIPA CHRM2 779/4885CHRM4 1780/4885CHRM5 1313/4885
US-20220062121-A1 MICROEMULSION COMPOSITION, CURED MATERIAL THEREOF, AND COSMETIC CONTAINING THE CURED MATERIAL MGLL, LIPA, MAN2B1 CHRM2 951/4885CHRM4 2679/4885CHRM5 2526/4885
US-10869828-B2 Cosmetic ALG1, ALG3, MGAT1 CHRM2 36/4885CHRM4 450/4885CHRM5 306/4885
US-20260053725-A1 COSMETIC PREPARATION CONTAINING CROSSLINKED ORGANIC SILICON RESIN AND METHOD FOR PRODUCING SAME ASH2L, L1CAM, RAD51 CHRM2 448/4885CHRM4 1500/4885CHRM5 859/4885
US-20260137603-A1 MULTILAYER MAKEUP PROTECTIVE COSMETIC CUTA, SMURF1, SMURF2 CHRM2 697/4885CHRM4 1264/4885CHRM5 601/4885
US-12478565-B2 Water-dispersion emulsion composition, method for manufacturing the same, emulsion addition-cured composition, and cosmetic CUTA, FANCD2, SMARCD1 CHRM2 991/4885CHRM4 2640/4885CHRM5 1780/4885
US-20190201317-A1 COSMETIC ALG1, ALG3, MGAT1 CHRM2 36/4885CHRM4 450/4885CHRM5 306/4885
US-20220387265-A1 WATER-DISPERSION EMULSION COMPOSITION, METHOD FOR MANUFACTURING THE SAME, EMULSION ADDITION-CURED COMPOSITION, AND COSMETIC CUTA, FANCD2, SMARCD1 CHRM2 991/4885CHRM4 2640/4885CHRM5 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.