SCHEMBL509089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5229379	0.94	KCNH2 (0.43)	KCNH2VNN1CYP2C9PARP15PARP10
	SCHEMBL5229495	0.91	KCNH2 (0.47)	KCNH2VNN1CYP2C9PARP15PARP10
	SCHEMBL5226693	0.91	KCNH2 (0.45)	KCNH2CYP3A4VNN1CYP2C9CYP2D6
	SCHEMBL5228154	0.90	CYP3A4 (0.40)	KCNH2CYP3A4VNN1CYP2C9PARP15
	SCHEMBL508578	0.89	KCNH2 (0.53)	KCNH2CYP3A4CYP2C9CYP2D6CACNA1G
	SCHEMBL5228111	0.89	KCNH2 (0.53)	KCNH2CYP3A4VNN1CYP2C9CYP2D6
	SCHEMBL509241	0.89	KCNH2 (0.45)	KCNH2CYP3A4CYP2C9CYP2D6P2RX7
	SCHEMBL5228148	0.88	KCNH2 (0.53)	KCNH2CYP3A4CYP2C9CYP2D6NPC1
	SCHEMBL5226676	0.88	VNN1 (0.47)	VNN1PARP15PARP10PARP2OPRM1
	SCHEMBL509107	0.86	KCNH2 (0.44)	KCNH2CYP3A4CYP2C9CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.