Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093762 | 0.97 | SLC6A3 (0.35) | SLC6A3SLC6A2SLC6A4CYP1A2CYP2D6 | |
| SCHEMBL5093741 | 0.83 | SLC6A2 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5088388 | 0.83 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5125529 | 0.82 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5093763 | 0.81 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5126221 | 0.80 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5088448 | 0.79 | CPN1 (0.36) | SLC6A3SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL5092701 | 0.79 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3763394 | 0.78 | LSS (0.38) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3769638 | 0.78 | ACHE (0.39) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306084-A1 | Substituted Amide Compounds | OPRK1, NAA50, ACMSD | SLC6A3 3945/4885SLC6A2 2372/4885SLC6A4 2704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.