Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609785 | 0.80 | ALDH1A1 (0.67) | ALDH1A1NPSR1ENPP1KDM4ESMN1; SMN2 | |
| SCHEMBL10887539 | 0.80 | ALDH1A1 (0.43) | EGLN2ALDH1A1NPSR1ENPP1KDM4E | |
| SCHEMBL4425907 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2HPGDGAA | |
| SCHEMBL609545 | 0.76 | KDM1A (0.44) | ALDH1A1NPSR1ENPP1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL31728199 | 0.74 | UBE2M (0.43) | EGLN2ALDH1A1NPSR1ENPP1KDM4E | |
| SCHEMBL3636753 | 0.71 | ALDH1A1 (0.42) | EGLN2ALDH1A1ENPP1KDM4ESMN1; SMN2 | |
| SCHEMBL5420423 | 0.70 | ALDH1A1 (0.44) | EGLN2ALDH1A1NPSR1ENPP1KDM4E | |
| SCHEMBL15063412 | 0.69 | GAA (0.47) | ALDH1A1NPSR1SMN1; SMN2MAPK1TSHR | |
| SCHEMBL1650004 | 0.68 | ALDH1A1 (0.49) | EGLN2ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL18077064 | 0.68 | EGLN2 (1.00) | EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618108-A2 | TRIAZOLO[1,5-A]PYRIMIDINES AND PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS A2A ADENOSINE RECEPTOR ANTAGONISTS | Biogen Idec MA Inc. (US) | 2006-01-25 | — | — | EP | claimed |
| WO-2004092171-A2 | TRIAZOLO[1,5-A]PYRIMIDINES AND PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS A2A ADENOSIN E RECEPTOR ANTAGONISTS | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | claimed |
| WO-2022189189-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2022-09-15 | — | — | WO | disclosed |
| US-20080070932-A1 | Triazolo[ 1,5-A] Pyrimidines And Pyrazolo[ 1,5-A] Pyrimidines And Methods Of Making And Using The Same | BIOGEN IDEC MA INC. | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070932-A1 | Triazolo[ 1,5-A] Pyrimidines And Pyrazolo[ 1,5-A] Pyrimidines And Methods Of Making And Using The Same | ADORA2B, ADORA2A, ADORA1 | EGLN2 4225/4885ALDH1A1 279/4885NPSR1 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.