Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5096130 | 1.00 | PFKFB3 (0.52) | PFKFB3CYSLTR2CYSLTR1CA2CA9 | |
| SCHEMBL5101941 | 0.81 | ENPP3 (0.46) | PFKFB3HDAC6KDM4EALDH1A1 | |
| SCHEMBL1386425 | 0.81 | ENPP3 (0.46) | PFKFB3HDAC6KDM4EALDH1A1 | |
| SCHEMBL5101980 | 0.80 | PFKFB3 (0.41) | PFKFB3CYSLTR2CYSLTR1CA2CA9 | |
| SCHEMBL1385852 | 0.80 | PFKFB3 (0.41) | PFKFB3CYSLTR2CYSLTR1CA2CA9 | |
| SCHEMBL27665265 | 0.80 | PFKFB3 (0.56) | PFKFB3CYSLTR2CYSLTR1CYP2C19HDAC6 | |
| SCHEMBL27684619 | 0.78 | PFKFB3 (0.51) | PFKFB3CYSLTR2CYSLTR1HDAC6KDM4E | |
| SCHEMBL5090111 | 0.77 | PFKFB3 (0.65) | PFKFB3CYSLTR2CYSLTR1HDAC6P4HB | |
| SCHEMBL5090108 | 0.77 | PFKFB3 (0.65) | PFKFB3CYSLTR2CYSLTR1HDAC6P4HB | |
| SCHEMBL10275157 | 0.77 | PFKFB3 (0.74) | PFKFB3CYSLTR2CYSLTR1CYP2C19HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | HSPB1, HSF1, HSPE1 | PFKFB3 3216/4885CYSLTR2 1261/4885CYSLTR1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.