Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 5/20 | 0.46 |
| ▸ | ALPL | P05186 | 5/20 | 0.46 |
| ▸ | XIAP | P98170 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386425 | 1.00 | ENPP3 (0.46) | ENPP3ALPLXIAPPOLBPFKFB3 | |
| SCHEMBL1384116 | 0.83 | ENPP3 (0.58) | ENPP3ALPLXIAPPFKFB3ALDH1A1 | |
| SCHEMBL5101980 | 0.81 | PFKFB3 (0.41) | POLBPFKFB3HDAC6 | |
| SCHEMBL1385852 | 0.81 | PFKFB3 (0.41) | POLBPFKFB3HDAC6 | |
| SCHEMBL5096130 | 0.81 | PFKFB3 (0.52) | PFKFB3ALDH1A1KDM4EHDAC6 | |
| SCHEMBL5096126 | 0.81 | PFKFB3 (0.52) | PFKFB3ALDH1A1KDM4EHDAC6 | |
| SCHEMBL5096089 | 0.73 | ALDH1A1 (0.48) | ENPP3ALPLXIAPALDH1A1KDM4E | |
| SCHEMBL5101983 | 0.69 | ENPP3 (0.52) | ENPP3ALPLXIAPPOLBALDH1A1 | |
| SCHEMBL1384115 | 0.67 | ENPP3 (0.56) | ENPP3ALPLXIAPALDH1A1KDM4E | |
| SCHEMBL5090125 | 0.65 | LMNA (0.49) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | claimed |
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | TORRENT PHARMACEUTICALS LTD. (IN) | 2008-08-28 | — | — | US | disclosed |
| EP-1748987-A2 | 2-PROPENE-1-ONES AS HSP 70 INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005097746-A2 | 2-PROPENE-1-ONES AS HSP 70 INDUCERS | TORRENT PHARMACEUTICALS LTD (IN) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207608-A1 | 2-Propene-1-Ones As Hsp 70 Inducers | HSPB1, HSF1, HSPE1 | ENPP3 4182/4885ALPL 3366/4885XIAP 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.