Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097666 | 0.89 | PPARA (0.42) | PPARGPPARAL3MBTL1PPARD | |
| SCHEMBL5088616 | 0.84 | MEN1 (0.44) | LMNA | |
| SCHEMBL5098762 | 0.84 | KDM4E (0.43) | PPARGPPARALMNAPPARD | |
| SCHEMBL5141934 | 0.83 | FFAR4 (0.45) | PPARGPPARAFFAR1LMNAL3MBTL1 | |
| SCHEMBL5093263 | 0.83 | SCN9A (0.43) | — | |
| SCHEMBL5090505 | 0.82 | PLA2G2A (0.48) | PPARG | |
| SCHEMBL5088654 | 0.81 | CYSLTR1 (0.45) | PPARGPPARAPPARD | |
| SCHEMBL5098674 | 0.81 | PLA2G2A (0.47) | — | |
| SCHEMBL5088530 | 0.81 | DHODH (0.42) | PPARG | |
| SCHEMBL5097600 | 0.78 | ALOX15 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |
| US-7470708-B2 | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2008-12-30 | — | — | US | disclosed |