Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88218 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EGLAKMT2AHTT | |
| Water SCHEMBL3902406 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAKMT2AHTT | |
| Hydrochloric Acid SCHEMBL6316692 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAKMT2AHTT | |
| SCHEMBL15384321 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KDM4EGLAKMT2AHTT | |
| SCHEMBL480553 | 0.69 | ATAD2 (0.39) | ALDH1A1KDM4EGLAKMT2APOLB | |
| SCHEMBL3056710 | 0.68 | ALDH1A1 (0.34) | ALDH1A1KDM4EGLAKMT2AHTT | |
| SCHEMBL28015366 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EGLAKMT2AHTT | |
| SCHEMBL9747188 | 0.67 | CASP6 (0.59) | ALDH1A1KDM4EKMT2APOLBMAPT | |
| SCHEMBL25980036 | 0.67 | ALDH1A1 (0.48) | ALDH1A1KDM4EGLAKMT2AHTT | |
| SCHEMBL28429328 | 0.67 | TSHR (0.46) | ALDH1A1KDM4EGLAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |