Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 6/20 | 0.60 |
| ▸ | RXRA | P19793 | 5/20 | 0.55 |
| ▸ | RXRB | P28702 | 5/20 | 0.55 |
| ▸ | CNR1 | P21554 | 8/20 | 0.49 |
| ▸ | RXRG | P48443 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105634 | 0.86 | CNR1 (0.64) | NR4A2CNR1KDM4ENPC1RAB9A | |
| SCHEMBL5102816 | 0.80 | CNR1 (0.56) | NR4A2CNR1KDM4ENPC1RAB9A | |
| SCHEMBL5098755 | 0.76 | NR4A2 (1.00) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL5106478 | 0.76 | CNR1 (0.64) | NR4A2RXRARXRBCNR1RXRG | |
| SCHEMBL5106144 | 0.75 | CNR1 (0.45) | NR4A2RXRARXRBCNR1CNR2 | |
| SCHEMBL5099479 | 0.75 | TSHR (0.59) | CNR1RAB9AALDH1A1TP53TSHR | |
| SCHEMBL3378535 | 0.74 | RXRA (0.56) | NR4A2RXRARXRBCNR1RXRG | |
| SCHEMBL11755172 | 0.73 | NR4A2 (0.58) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL8555990 | 0.72 | NR4A2 (0.62) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL8552633 | 0.72 | NR4A2 (0.62) | NR4A2RXRARXRBRXRGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320978-B2 | Oxazole derivatives, preparation and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2008-01-22 | — | — | US | disclosed |
| US-20070043060-A1 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043060-A1 | OXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | OXA1L, ARG2, CYP3A7 | NR4A2 1444/4885RXRA 1094/4885RXRB 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.