Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466427 | 1.00 | MAPT (0.36) | MAPTABCB1MEN1KMT2AGAA | |
| SCHEMBL15341148 | 0.94 | MAPT (0.33) | MAPTABCB1MEN1KMT2ACYP1A2 | |
| SCHEMBL15341149 | 0.91 | MAPT (0.35) | MAPTABCB1MEN1KMT2AGAA | |
| SCHEMBL509000 | 0.91 | ABCB1 (0.39) | MAPTABCB1MEN1KMT2AGAA | |
| SCHEMBL509001 | 0.91 | ABCB1 (0.39) | MAPTABCB1MEN1KMT2AGAA | |
| SCHEMBL15341147 | 0.88 | MAPT (0.36) | MAPTABCB1MEN1KMT2AGAA | |
| SCHEMBL12481337 | 0.85 | ABCB1 (0.32) | ABCB1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL12481334 | 0.85 | ABCB1 (0.32) | ABCB1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL919585 | 0.85 | ABCB1 (0.42) | MAPTABCB1KMT2AGAAKDM4E | |
| SCHEMBL12481619 | 0.84 | ABCB1 (0.31) | ABCB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096533-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9096534-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-08-04 | — | — | US | disclosed |
| US-9029295-B2 | Pyridazinone compound and herbicide and noxious arthropod controlling agent comprising it | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2015-05-07 | — | — | US | disclosed |
| US-8962625-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130281299-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | SUMITOMO CHEMICAL COMPANY,LIMITED (JP) | 2013-10-24 | — | — | US | disclosed |
| US-8541414-B2 | Pyridazinone compound and use thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-09-24 | — | — | US | disclosed |
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | KIJI TOSHIYUKI (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20110319266-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20100298142-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | MAPT 4297/4885ABCB1 4546/4885MEN1 806/4885 |
| US-20110319266-A1 | HERBICIDAL COMPOSITION | DDT, EGLN1, ELF3 | MAPT 3582/4885ABCB1 2092/4885MEN1 1251/4885 |
| US-20100248964-A1 | HERBICIDAL COMPOSITION | CHRM2, CHRM1, WEE1 | MAPT 4336/4885ABCB1 2961/4885MEN1 4148/4885 |
| US-20150126738-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | MAPT 3369/4885ABCB1 1544/4885MEN1 4206/4885 |
| US-20100210462-A1 | HERBICIDAL COMPOSITION | WEE1, WEE2, H1-3 | MAPT 4413/4885ABCB1 2169/4885MEN1 4076/4885 |
| US-20150126739-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | MAPT 3369/4885ABCB1 1544/4885MEN1 4206/4885 |
| US-20120196750-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | PDXK, PLPBP, PNPO | MAPT 3369/4885ABCB1 1544/4885MEN1 4206/4885 |
| US-20130281299-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT | ACHE, CBR3, DDT | MAPT 4682/4885ABCB1 4554/4885MEN1 4347/4885 |
| US-20090111696-A1 | Pyridazinone Compound and Use Thereof as herbicides | PDXK, DDT, PLPBP | MAPT 3414/4885ABCB1 1517/4885MEN1 4455/4885 |
| US-20100298142-A1 | HERBICIDAL COMPOSITION | CYP2W1, WEE2, CYP2J2 | MAPT 4587/4885ABCB1 1820/4885MEN1 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.