Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60866 | 0.80 | KDM4E (0.56) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL31645245 | 0.78 | IKBKB (0.49) | ALDH1A1SMN1; SMN2CYP3A4KDM4C | |
| SCHEMBL28247144 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2KDM4C | |
| SCHEMBL5096070 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2CDK9 | |
| SCHEMBL5096004 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2CDK9 | |
| SCHEMBL18285376 | 0.76 | TDP1 (0.47) | KDM4EALDH1A1HPGDNPC1MAPT | |
| SCHEMBL29574749 | 0.73 | PDE5A (0.49) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL22717545 | 0.73 | PDE5A (0.49) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL5102002 | 0.73 | ALOX15 (0.66) | MAOAKDM4EALDH1A1ALOX15ECE1 | |
| SCHEMBL9318744 | 0.71 | NQO2 (0.50) | PDGFRBPDGFRAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207677-A1 | Napthyridine Compounds As Rock Inhibitors | GPC BIOTECH AG (DE) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207677-A1 | Napthyridine Compounds As Rock Inhibitors | ROCK2, ROCK1, RHOT2 | MAOA 1659/4885PDGFRB 3216/4885PDGFRA 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.